Ketogenic diet as a metabolic therapy for mood disorders: Evidence and developments

Despite significant advances in pharmacological and non-pharmacological treatments, mood disorders remain a significant source of mental capital loss, with high rates of treatment resistance, requiring a coordinated effort in investigation and development of efficient, tolerable and accessible novel interventions. Ketogenic diet (KD) is a low-carb diet that substantially changes the energetic matrix of the body […]

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The ketogenic diet as a potential treatment and prevention strategy for Alzheimer’s disease

The prevalence of Alzheimer’s disease, a chronic neurodegenerative condition, is increasing as is the need for effective treatments and preventions. The underlying pathology of Alzheimer’s is not yet fully understood, so existing research has focused on understanding the prominent features of the disease. These include amyloid plaques, which accumulate in the brains of those with […]

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Timing of food intake is more potent than habitual voluntary exercise to prevent diet-induced obesity in mice

Inappropriate eating habits such as eating late at night are associated with risk for abnormal weight-gain and adiposity. We previously reported that time-imposed feeding during the daytime (inactive phase) induces obesity and metabolic disorders accompanied by physical inactivity in mice. The present study compares metabolic changes induced in mice by time-imposed feeding under voluntary wheel-running […]

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Stress Raises Cholesterol Levels

It appears so for some people, according to a new study that examines how reactions to stress over a period of time can raise a person’s lipid levels. This finding is reported in the November issue of¬†Health Psychology, published by the American Psychological Association (APA). In a sample of 199 healthy middle-aged men and women, […]

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Oxidative Stress Inhibits Healthy Adipose Expansion

Recent studies have emphasized the association of adipose oxidative stress (Fat ROS) with the pathogenesis of metabolic disorders in obesity. However, the causal roles of Fat ROS in metabolic disturbances¬†in vivoremain unclear because no mouse model has been available in which oxidative stress is manipulated targeting adipocytes. In this research, we generated two models of […]

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