Consumption of added sugars among U.S. adults, 2005-2010

Increased consumption of added sugars, which are sweeteners added to processed and prepared foods, has been linked to a decrease in intake of essential micronutrients and an increase in body weight. The Dietary Guidelines for Americans, 2010 recommends limiting total intake of discretionary calories, including both added sugars and solid fats, to 5%-15% per day. […]

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Sugar addiction: Is it real?

In animal studies, sugar has been found to produce more symptoms than is required to be considered an addictive substance. Animal data has shown significant overlap between the consumption of added sugars and drug-like effects, including bingeing, craving, tolerance, withdrawal, cross-sensitisation, cross-tolerance, cross-dependence, reward and opioid effects. Sugar addiction seems to be dependence to the […]

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Examining the Health Effects of Fructose

In the 1990s, excessive fat consumption was commonly believed to be the main cause of obesity. High sugar consumption was often considered to be innocuous and possibly protective against obesity by displacing dietary fat. A decade later, the American Heart Association linked intake of added sugars to weight gain and recommended substantial decreases in consumption […]

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Evidence Behind the Advice About Salt

Low-sodium diets are widely recommended for people who have a variety of ailments, but there’s little proof they help those with heart failure. Despite a number of studies questioning the usefulness of very low-salt diets in the last few years, most major medical organizations continue to recommend them. We would assume that they do so from a strong base of evidence. […]

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Obesity: Replacing Bias With Curiosity

Visualize a woman with obesity. Do you assume she eats all day and never gets off the couch? Picture a man with obesity. Do you think of him as lazy and unsuccessful? Are you secretly (or not so secretly) critical of those you love who have obesity? Do you yourself live with obesity, self-judgment, and shame? When we […]

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Eating Particular Diets Can Help Heal Us

Between 2016 and 2018, postdoctoral researchers in Cantley’s laboratory and mine established that this strategy worked on several mouse cancers, and on human cancers implanted into mice. By 2019, working with clinicians at Columbia, Cornell and Memorial Sloan Kettering, we hope to begin a study in humans with lymphomas, endometrial cancer and breast cancer, to […]

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Ketogenic Diet Shows Promising Results for All Dementia Stages

Studies show a ketogenic diet can slow and even reverse symptoms of memory loss and cognitive impairment throughout all the dementia stages. You might be asking, “What is a ketogenic diet?” A ketogenic diet is a high-fat, adequate-protein, and low-carbohydrate diet that produces ketones—compounds the body can use to produce energy. Ketones have been shown in studies […]

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Evaluation of the Concurrent Trajectories of Cardiometabolic Risk Factors in the 14 Years Before Dementia

Cardiometabolic risk factors have been associated with an increased risk of dementia; yet, the optimal targets and time window for the management of cardiometabolic health to prevent dementia remain unknown. OTo model concurrently and compare the trajectories of cardiometabolic risk factors up to 14 years preceding diagnosis in individuals with dementia and matched controls free […]

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Estimation of Global Insulin Use for Type 2 Diabetes, 2018–30

The amount of insulin needed to effectively treat type 2 diabetes worldwide is unknown. It also remains unclear how alternative treatment algorithms would affect insulin use and disability-adjusted life-years (DALYs) averted by insulin use, given that current access to insulin (availability and affordability) in many areas is low. The aim of this study was to […]

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Worldwide Obesity Dynamics and Their Determinants

Review of results of the study is focusing on large-scale surveys and nationally representative studies of diet, activity, and obesity among adults and children. The study was conducted with youth and adults from a range of countries around the world. Task Force guidelines for defining overweight and obesity are used for youth and the body […]

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