Association Between Blood Glucose Variability and Coronary Plaque Instability

Blood glucose variability is receiving considerable attention as a new risk factor for coronary artery disease. This study aimed to investigate the association between blood glucose variability and coronary plaque tissue characteristics. Cardiovascular Diabetology: Association between blood glucose variability and coronary plaque instability in patients with acute coronary syndromes Methods In 57 patients with acute coronary […]

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The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy

Recent evidence suggests that Parkinson’s disease (PD) is associated with intestinal microbiota dysbiosis, abnormal intestinal permeability, and intestinal inflammation. Publimed: The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy OBJECTIVE: Our study aimed to determine if these gut abnormalities are present in another synucleinopathy, multiple system atrophy (MSA). METHODS: In six MSA and 11 healthy […]

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Short-Term Fasting Induces Profound Neuronal Autophagy

Disruption of autophagy—a key homeostatic process in which cytosolic components are degraded and recycled through lysosomes—can cause neurodegeneration in tissue culture and in vivo. Upregulation of this pathway may be neuroprotective, and much effort is being invested in developing drugs that cross the blood brain barrier and increase neuronal autophagy. PMC: Short-term fasting induces profound neuronal […]

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Statins stimulate atherosclerosis and heart failure: pharmacological mechanisms

In contrast to the current belief that cholesterol reduction with statins decreases atherosclerosis, we present a perspective that statins may be causative in coronary artery calcification and can function as mitochondrial toxins that impair muscle function in the heart and blood vessels through the depletion of coenzyme Q10 and ‘heme A’, and thereby ATP generation. […]

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“Dirty Dozen” and “Clean Fifteen” Lists

The Environmental Working Group (EWG) recently released its 2017 “Dirty Dozen” and “Clean Fifteen” lists — a catalog of fruits and vegetables with the highest and lowest amounts of pesticide residue. Strawberries still top the “Dirty Dozen” list — in fact, one sample of strawberries had more than 20 different pesticides. The increased insect burden […]

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Pediatricians Advise Parents: No Fruit Juice In the Child’s First Year

The nation’s top pediatricians are advising parents to stop giving fruit juice to children in the first year of life, saying the drink is not as healthful as many parents think. The New  York Times: Pediatricians Say No Fruit Juice in Child’s First Year In the past, the American Academy of Pediatrics had advised parents to […]

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FDA warns of foot, leg amputations with J&J diabetes drug

Johnson & Johnson is required to add new warnings to its diabetes drug, Invokana, about the risk of foot and leg amputations, the U.S. Food and Drug Administration said on Tuesday. Reuters: FDA warns of foot, leg amputations with J&J diabetes drug Final results from two clinical trials showed leg and foot amputations occurred about twice as […]

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Adrenal Fatigue Explained

Cortisol, DHEA, and another hormone, adrenaline, are the three main hormones secreted by the adrenal glands in response to stress. In the short run, they provide protection to the body against a variety of threats—anything perceived by the unconscious brain as potentially dangerous—from infection to a hungry lion, particularly if you happen to be a […]

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Carbohydrate Restriction in Cancer Therapy

Dr. Dawn Lemanne is a Stanford-trained, board-certified integrative and medical oncologist. Dr. Lemanne has published in peer-reviewed journals and has authored textbook chapters in integrative oncology. She holds degrees in biophysics, public health, medicine, and science writing from the University of California, Berkeley, the University of California, San Francisco, and Johns Hopkins University. In 2016, […]

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