Is Hepatic de Novo Lipogenesis Leading to Metabolic Syndrome and Associated Chronic Diseases?

Epidemiologic studies suggest a link between excess sugar consumption and obesity, fatty liver disease, metabolic syndrome, and type 2 diabetes mellitus. The Journal of the American Osteopathic Association: Conversion of Sugar to Fat: Is Hepatic de Novo Lipogenesis Leading to Metabolic Syndrome and Associated Chronic Diseases? One important pathway that may link these metabolic diseases to […]

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Low-Calorie Diet May Slow Aging

New research has revealed that as mice age, the biological clock in their stem cells remains just as active but shifts focus onto other cell processes. It becomes less concerned with maintaining tissue and more involved in dealing with stress, carrying out such functions as repairing damaged DNA. MedicalNews: Low-calorie diet may slow aging by ‘rejuvenating […]

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Glucose Metabolism in Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disorder characterized by bilateral renal cyst formation. Publimed: Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy. Recent identification of signaling cascades deregulated in ADPKD has led to the initiation of several clinical trials, but an approved therapy is still lacking. Using a […]

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Exercise: Is More Always Better?

Animals that acquire, assimilate, and metabolize energy from food and can use these available energy sources to successfully reproduce are positioned for optimal survival. Current Biology: Exercise: Is More Always Better? Flexibility is an important feature of this biological construct that allows animals and other organisms to adjust as energy availability waxes and wanes with varying food resources and metabolic […]

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Too Much Sugar Could Increase Depression Risk in Men

Men who consume a lot of added sugar in drinks, cakes and confectionery run an increased risk of depression, according to a new study. The Guardian: Too much sugar could increase depression risk in men, study suggests Researchers from University College London (UCL) looked at sugar in the diet and common mental health problems in a […]

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Ketogenic Diets for Psychiatric Disorders

If you have a brain, you need to know about ketogenic diets. The fact that these specially-formulated low-carbohydrate diets have the power to stop seizures in their tracks is concrete evidence that food has a tremendous impact on brain chemistry and should inspire curiosity about how they work. I first became interested in ketogenic diets as […]

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Dr. Gary Fettke – ‘Nutrition and Inflammation’

Dr. Gary Fettke is an Orthopaedic Surgeon and Senior Lecturer at the University of Tasmania practising in Launceston, Australia. Along with his wife Belinda, Gary has also opened the ‘Nutrition for Life – Diabetes and Health Research Centre’ based in Launceston which provides nutritional care around Tasmania and Australia. Gary has a longstanding interest in […]

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Comparison of A Low-Fat Diet to A Low-Carbohydrate Diet on Risk Factor for Diabetes and Cardiovascular Disease

40 overweight individuals were randomized to a low-carb and a low-fat diet for 10 weeks. The calories were matched between groups. Weight Loss: The low-carb group lost 7.0 kg (15.4 lbs) and the low-fat group lost 6.8 kg (14.9 lbs). The difference was not statistically significant. Conclusion: Both groups lost a similar amount of weight. […]

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A Low-Carbohydrate as Compared with a Low-Fat Diet in Severe Obesity

Details: 132 individuals with severe obesity (mean BMI of 43) were randomized to either a low-fat or a low-carb diet. Many of the subjects had metabolic syndrome or type II diabetes. The low-fat dieters were calorie restricted. Study duration was 6 months. Weight Loss: The low-carb group lost an average of 5.8 kg (12.8 lbs) […]

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