Comparison of A Low-Fat Diet to A Low-Carbohydrate Diet on Risk Factor for Diabetes and Cardiovascular Disease

40 overweight individuals were randomized to a low-carb and a low-fat diet for 10 weeks. The calories were matched between groups. Weight Loss: The low-carb group lost 7.0 kg (15.4 lbs) and the low-fat group lost 6.8 kg (14.9 lbs). The difference was not statistically significant. Conclusion: Both groups lost a similar amount of weight. […]

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A Low-Carbohydrate as Compared with a Low-Fat Diet in Severe Obesity

Details: 132 individuals with severe obesity (mean BMI of 43) were randomized to either a low-fat or a low-carb diet. Many of the subjects had metabolic syndrome or type II diabetes. The low-fat dieters were calorie restricted. Study duration was 6 months. Weight Loss: The low-carb group lost an average of 5.8 kg (12.8 lbs) […]

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The Health Benefits of Ubuiquinol

There are many coenzymes. Among the most important is called Coenzyme Q10, or CoQ10. This vitamin-like substance is made naturally in the body and plays a critical role in the creation of cellular energy. It’s no surprise, then, that lots of CoQ10 is found inside the tissue of energy-demanding organs such as the heart, brain, […]

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The Deadly Effects of Fructose

In 2009, Dr. Robert Lustig, a pediatric endocrinologist at the University of California, San Francisco delivered a ninety minute lecture entitled “Sugar: The Bitter Truth”. It was posted on YouTube as part of the university’s medical education series. Then a funny thing happened. It went viral. Medium: The Deadly Effects of Fructose It was not a humorous […]

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Ketogenic Diet for Diabetes

When patients are diagnosed with type 2 diabetes, clinicians stress lifestyle modifications—and especially diet—as the first and best intervention. Often, they recommend diets endorsed by the American Diabetes Association. Pharmacy Times:  Ketogenic Diet for Diabetes: Recent Research Shows Good Results  A previous study suggested that a very low-carbohydrate ketogenic diet augmented with more physical activity, […]

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Association Between Blood Glucose Variability and Coronary Plaque Instability

Blood glucose variability is receiving considerable attention as a new risk factor for coronary artery disease. This study aimed to investigate the association between blood glucose variability and coronary plaque tissue characteristics. Cardiovascular Diabetology: Association between blood glucose variability and coronary plaque instability in patients with acute coronary syndromes Methods In 57 patients with acute coronary […]

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The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy

Recent evidence suggests that Parkinson’s disease (PD) is associated with intestinal microbiota dysbiosis, abnormal intestinal permeability, and intestinal inflammation. Publimed: The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy OBJECTIVE: Our study aimed to determine if these gut abnormalities are present in another synucleinopathy, multiple system atrophy (MSA). METHODS: In six MSA and 11 healthy […]

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Short-Term Fasting Induces Profound Neuronal Autophagy

Disruption of autophagy—a key homeostatic process in which cytosolic components are degraded and recycled through lysosomes—can cause neurodegeneration in tissue culture and in vivo. Upregulation of this pathway may be neuroprotective, and much effort is being invested in developing drugs that cross the blood brain barrier and increase neuronal autophagy. PMC: Short-term fasting induces profound neuronal […]

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Statins stimulate atherosclerosis and heart failure: pharmacological mechanisms

In contrast to the current belief that cholesterol reduction with statins decreases atherosclerosis, we present a perspective that statins may be causative in coronary artery calcification and can function as mitochondrial toxins that impair muscle function in the heart and blood vessels through the depletion of coenzyme Q10 and ‘heme A’, and thereby ATP generation. […]

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“Dirty Dozen” and “Clean Fifteen” Lists

The Environmental Working Group (EWG) recently released its 2017 “Dirty Dozen” and “Clean Fifteen” lists — a catalog of fruits and vegetables with the highest and lowest amounts of pesticide residue. Strawberries still top the “Dirty Dozen” list — in fact, one sample of strawberries had more than 20 different pesticides. The increased insect burden […]

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