No Significant Association with Dairy Fat Intake and Heart Disease

Controversy has emerged about the benefits compared with harms of dairy fat, including concerns over long-term effects. Previous observational studies have assessed self-reported estimates of consumption or a single biomarker measure at baseline, which may lead to suboptimal estimation of true risk. The aim of this study was to investigate prospective associations of serial measures […]

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Dietary Intake of Menaquinone Is Associated with a Reduced Risk of Coronary Heart Disease: The Rotterdam Study

Vitamin K–dependent proteins, including matrix Gla-protein, have been shown to inhibit vascular calcification. Activation of these proteins via carboxylation depends on the availability of vitamin K. We examined whether dietary intake of phylloquinone (vitamin K-1) and menaquinone (vitamin K-2) were related to aortic calcification and coronary heart disease (CHD) in the population-based Rotterdam Study. The […]

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‘Carbohydrates are killing us’

This year, more than 610,000 Americans will die from heart disease. It’s the leading cause of death for both men and women. For decades, doctors and nutritionists prescribed low-fat diets to people trying to lower their risk of heart disease. Saturated fats in meats and dairy products were thought to clog our arteries. Grains — […]

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Genetic Study Supports Carbohydrate-Insulin Model of Obesity

According to the Carbohydrate-Insulin Model of Obesity (CIM), the processed carbohydrates that flooded our diet during the low-fat diet craze undermine our metabolism and drive weight gain. Put simply: Processed carbohydrates — think white bread, white rice, potato products, low -fat snacks — raise insulin more than any other food, calorie for calorie. This is just Nutrition, 101. Insulin is the Miracle-Gro […]

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Man loses over 300 pounds on a low-carb diet

Tony has lost an impressive 326 lbs (148 kg) following a low-carb high-protein diet and walking. Congratulations! His weight-loss journey started in May 2016 after the wildfire in Fort McMurray. At this time, he had to use two airplane seats during the evacuation, delaying other people from getting to safety. This increased his motivation to attempt a […]

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Dr. Maryanne Demasi – ‘Statin Wars: Have we been misled by the evidence?’

Dr. Maryanne Demasi is a former medical scientist who completed her PhD in Medicine at the University of Adelaide. Her research focused on the pathology of Rheumatoid arthritis and potential therapies. Her innovative research has appeared in several internationally published medical journals. Leaving her lab coat behind, Maryanne accepted a position as a political advisor […]

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Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets

Very-low-carbohydrate diets or ketogenic diets have been in use since the 1920s as a therapy for epilepsy and can, in some cases, completely remove the need for medication. From the 1960s onwards they have become widely known as one of the most common methods for obesity treatment. Recent work over the last decade or so […]

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Exercise Training Improves the Insulin Sensitivity

It is not known whether the beneficial effects of exercise training on insulin sensitivity are due to changes in hepatic and peripheral insulin sensitivity or whether the changes in insulin sensitivity can be explained by adaptive changes in fatty acid metabolism, changes in visceral fat or changes in liver and muscle triacylglycerol content. We investigated […]

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Supra-Additive Effects of Combining Fat and Carbohydrate on Food Reward

Fat and carbohydrate interact to potentiate reward independently of liking. This is reflected in supra-additive responses in the striatum during food valuation. Participants are able to estimate energy density from fat, but not carbohydrate. Accurate estimation of energy density recruits a prefrontal-fusiform gyrus circuit Post-ingestive signals conveying information about the nutritive properties of food are […]

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Effects of medium-chain triglycerides on weight loss and body compositio

Medium-chain triglycerides (MCTs) may result in negative energy balance and weight loss through increased energy expenditure and lipid oxidation. However, results from human intervention studies investigating the weight reducing potential of MCTs, have been mixed. To conduct a systematic review and meta-analysis of randomized controlled trials comparing the effects of MCTs, specifically C8:0 and C10:0, […]

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