Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets

Very-low-carbohydrate diets or ketogenic diets have been in use since the 1920s as a therapy for epilepsy and can, in some cases, completely remove the need for medication. From the 1960s onwards they have become widely known as one of the most common methods for obesity treatment. Recent work over the last decade or so […]

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Robert Lustig, MD, What is Metabolic Syndrome, and Why are Children Getting It?

A grouping of health conditions associated with an increased risk for heart disease and type 2 diabetes. Conditions include hypertension, a large waist, high triglyceride levels, low HDL cholesterol levels, and above-normal blood glucose levels.

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Carbohydrates Are Killing Us

This year, more than 610,000 Americans will die from heart disease. It’s the leading cause of death for both men and women. For decades, doctors and nutritionists prescribed low-fat diets to people trying to lower their risk of heart disease. Saturated fats in meats and dairy products were thought to clog our arteries. Grains — […]

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Not getting enough sleep seems to be even more deadly than we thought, new studies show

A trio of new studies show that too little or too much sleep is associated with an increased risk for cardiovascular disease.  Sleeping less than five hours per night raises the risk for a heart attack or stroke by about the same degree as smoking does, according one study in older men. This adds to a significant body of evidence that […]

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Heart attacks at strokes ‘set to soar 30% due to diabetes epidemic’

Patients with type 2 diabetes were two to four times more likely to have a heart attack or stroke, the British Heart Foundation said,  Heart attacks and strokes will rocket over the coming years as the diabetes epidemic sweeping the nation takes its toll, a charity has warned. The increase could be as high as […]

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Statins stimulate atherosclerosis and heart failure

Harumi Okuyama outlines the research that lead to his paper that argues statins stimulate atherosclerosis and heart failure. ‘Statins stimulate atherosclerosis and heart failure: pharmacological mechanisms’ published in Expert Review of Clinical Pharmacology in February 2015. Our review on cholesterol-lowering drugs, statins, was published in the Expert Review of Clinical Pharmacology in 2015, and had been downloaded from the journal […]

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No Significant Association with Dairy Fat Intake and Heart Disease

Controversy has emerged about the benefits compared with harms of dairy fat, including concerns over long-term effects. Previous observational studies have assessed self-reported estimates of consumption or a single biomarker measure at baseline, which may lead to suboptimal estimation of true risk. The aim of this study was to investigate prospective associations of serial measures […]

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Vitamin K Dependent Proteins and the Role of Vitamin K2 in the Modulation of Vascular Calcification: A Review

Vascular calcification, a cause of cardiovascular morbidity and mortality, is an actively regulated process involving vitamin K dependent proteins (VKDPs) among others. Vitamin K is an essential micronutrient, present in plants and animal fermented products that plays an important role as a cofactor for the post-translational γ-carboxylation of glutamic acid residues in a number of […]

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Dietary Intake of Menaquinone Is Associated with a Reduced Risk of Coronary Heart Disease: The Rotterdam Study

Vitamin K–dependent proteins, including matrix Gla-protein, have been shown to inhibit vascular calcification. Activation of these proteins via carboxylation depends on the availability of vitamin K. We examined whether dietary intake of phylloquinone (vitamin K-1) and menaquinone (vitamin K-2) were related to aortic calcification and coronary heart disease (CHD) in the population-based Rotterdam Study. The […]

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Juice Is Not Healthy

Obesity affects 40 percent of adults and 19 percent of children in the United States and accounts for more than $168 billion in health care spendingeach year. Sugary beverages are thought to be one of the major drivers of the obesity epidemic. These drinks (think soda and sports drinks) are the largest single source of added sugars for Americans and contribute, on […]

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