Ketogenic Diet as a Metabolic Therapy for Mood Disorders

Despite significant advances in pharmacological and non-pharmacological treatments, mood disorders remain a significant source of mental capital loss, with high rates of treatment resistance, requiring a coordinated effort in investigation and development of efficient, tolerable and accessible novel interventions. Ketogenic diet (KD) is a low-carb diet that substantially changes the energetic matrix of the body […]

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Microbial regulation of microRNA expression in the amygdala and prefrontal cortex

There is growing evidence for a role of the gut microbiome in shaping behaviour relevant to many psychiatric and neurological disorders. Preclinical studies using germ-free (GF) animals have been essential in contributing to our current understanding of the potential importance of the host microbiome for neurodevelopment and behaviour. In particular, it has been repeatedly demonstrated […]

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Antidepressant Use May Contribute to Long-Term Population Weight Gain

Researchers at King’s College London have found that patients prescribed any of the 12 most commonly used antidepressants were 21% more likely to experience an episode of gain weight than those not taking the drugs, (after adjusting for other factors which might affect this result). The full research is published in the BMJ. They also found […]

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What Will Happen to Your Body If You Walk Every Day

Walking is a totally free, easy exercise that requires little effort, and benefits not only your physical but also your mental well-being. If you’re looking for a simple yet very effective way of losing weight and improving your overall health, walking is something just for you. People who are physically active throughout their life are […]

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CarbLoaded: A Culture Dying to Eat

The film traces the origins of our beliefs about healthful and unhealthful food. Experts from all over the world talk about the problems as well as short and long term solutions. Among the many experts in the film are authors like Gary Taubes, Mark Sisson, and Melanie Warner. Medical doctors such as David Perlmutter M.D., […]

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Food Prices and Body Fatness Among Youths

We examine the effect of food prices on clinical measures of obesity, including body mass index (BMI) and percentage body fat (PBF) measures derived from bioelectrical impedance analysis (BIA) and dual energy X-ray absorptiometry (DXA), among youths ages 12 through 18 in the National Health and Nutrition Examination Survey. This is the first study to […]

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Outcome Age-Based Prediction of Successful Cognitive Aging by Total Cholesterol

Total cholesterol and cognition associations differ in studies at different outcome ages. Some associations of cholesterol with cognition diminish as outcome age increases. In the oldest-old, some relationships reverse from younger elderly samples. Studies seeking protection should focus on good cognition despite high risk. Some associations of high total cholesterol with dementia risk diminish as […]

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Effect of Depression and Diabetes on the Risk for Dementia

Although depression and type 2 diabetes mellitus (DM) may independently increase the risk for dementia, no studies have examined whether the risk for dementia among people with comorbid depression and DM is higher than the sum of each exposure individually. It was  performed a national population-based cohort study of 2 454 532 adults, including 477 133 (19.4%) with […]

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Study Shows Stress Could Be Just as Unhealthy as Junk Food

We all know that a poor diet is unhealthy, but a new BYU study finds that stress may be just as harmful to our bodies as a really bad diet. In a new paper published in Nature Scientific Reports, BYU professor of microbiology and molecular biology Laura Bridgewater found that when female mice were exposed to […]

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The Nervous System and Metabolic Dysregulation

A link between metabolism and brain function is clear. Since ancient times, epileptic seizures were noted as treatable with fasting, and historical observations of the therapeutic benefits of fasting on epilepsy were confirmed nearly 100 years ago. Shortly thereafter a high fat, low-carbohydrate ketogenic diet (KD) debuted as a therapy to reduce seizures. This strict regimen […]

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