Spoonful of Sugar Helps the Sales Go Up

Out: protein and fewer carbs. In: unicorn-shaped marshmallows. It’s a ‘permissible indulgence’ To get consumers to eat cereal, big food companies are doubling down on sugary goodness. Lucky Charms Frosted Flakes from General Mills Inc. and Chocolate Frosted Flakes from Kellogg Co. are among the industry’s latest answers to the persistent decline in cereal sales. For […]

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Triglycerides cross the blood–brain barrier and induce central leptin and insulin receptor resistance

Resistance at the brain receptors for leptin and insulin has been associated with increased feeding, obesity and cognitive impairments. The causal agent for central resistance is unknown but could be derived from the blood. Here we postulate whether hypertriglyceridemia, the major dyslipidemia of the metabolic syndrome, could underlie central leptin and insulin resistance. We used […]

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Link Between Sugar and Alzheimer’s

The aim of the study was to evaluate longitudinal associations between HbA1c levels, diabetes status and subsequent cognitive decline over a 10 year follow-up period. Data from wave 2 (2004–2005) to wave 7 (2014–2015) of the English Longitudinal Study of Ageing (ELSA) were analysed. Cognitive function was assessed at baseline (wave 2) and reassessed every 2 years at […]

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Obesity-Related Hospital Admissions Double in Four Years

The number of obesity-related hospital admissions has more than doubled in the last four years with obese women in particular placing an increasing burden on the NHS, new figures show. There were almost 617,000 appointments in 2016-17 where obesity was either a primary or secondary diagnosis – up from 292,000 in 2012-13. Two in every […]

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Trends in Obesity and Severe Obesity Prevalence in US Youth and Adults by Sex and Age, 2007-2008 to 2015-2016

Obesity prevalence has been increasing since the 1980s among adults, but among youth, prevalence plateaued between 2005-2006 and 2013-2014.1,2 We analyzed trends in obesity prevalence among US youth and adults between 2007-2008 and 2015-2016 in order to determine recent changes. Methods The National Health and Nutrition Examination Survey (NHANES) is a cross-sectional survey with a complex, […]

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Global Correlates of Cardiovascular Risk: A Comparison of 158 Countries

The aim of this study was a large-scale ecological analysis of nutritional and other environmental factors potentially associated with the incidence of cardiovascular diseases (CVDs) in the global context. Indicators of CVDs from 158 countries were compared with the statistics of mean intake (supply) of 60 food items between 1993 and 2011, obesity rates, health […]

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Fasting and Insulin resistance

Dr. Jason Fung completed medical school and internal medicine at the University of Toronto before finishing his nephrology fellowship at the University of California, Los Angeles at the Cedars-Sinai hospital. He now has a practice in Ontario, Canada where he uses his Intensive Dietary Management program to help all sorts of patients, but especially those […]

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Widowmaker TV Version

Note that the fixes for cardiovascular disease primarily involve lowering hyperinsulinemia (mainly via a well-formulated LCHF diet), adequate Magnesium, optimum Omega3:Omega6 ratio, adequate sun exposure/vitamin D and many others. The movie here mainly mentioned meds, a very small part of the risk-reversal story.

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Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders

High-fat, low-carbohydrate diets, known as ketogenic diets, have been used as a non-pharmacological treatment for refractory epilepsy. A key mechanism of this treatment is thought to be the generation of ketones, which provide brain cells (neurons and astrocytes) with an energy source that is more efficient than glucose, resulting in beneficial downstream metabolic changes, such as increasing adenosine levels, which might […]

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Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders

High-fat, low-carbohydrate diets, known as ketogenic diets, have been used as a non-pharmacological treatment for refractory epilepsy. A key mechanism of this treatment is thought to be the generation of ketones, which provide brain cells (neurons and astrocytes) with an energy source that is more efficient than glucose, resulting in beneficial downstream metabolic changes, such as increasing adenosine levels, which might […]

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