The Nervous System and Metabolic Dysregulation

A link between metabolism and brain function is clear. Since ancient times, epileptic seizures were noted as treatable with fasting, and historical observations of the therapeutic benefits of fasting on epilepsy were confirmed nearly 100 years ago. Shortly thereafter a high fat, low-carbohydrate ketogenic diet (KD) debuted as a therapy to reduce seizures. This strict regimen […]

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How the Food You Eat Affects Your Brain

When it comes to what you bite, chew and swallow, your choices have a direct and long-lasting effect on the most powerful organ in your body: your brain. So which foods cause you to feel so tired after lunch? Or so restless at night? Mia Nacamulli takes you into the brain to find out.

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How Sugar Affects the Brain

When you eat something loaded with sugar, your taste buds, your gut and your brain all take notice. This activation of your reward system is not unlike how bodies process addictive substances such as alcohol or nicotine — an overload of sugar spikes dopamine levels and leaves you craving more. Nicole Avena explains why sweets […]

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High-Fat Ketogenic Diet Effectively Treats Childhood Seizures

The high-fat ketogenic diet can dramatically reduce or completely eliminate debilitating seizures in most children with infantile spasms, whose seizures persist despite medication, according to a Johns Hopkins Children’s Center study published online April 30 in the journal Epilepsia. ScienceDaily: High-fat ketogenic diet effectively treats persistent childhood seizures, study finds Infantile spasms, also called West syndrome, is […]

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Reverse Engineering Epilepsy’s ‘Miracle’ Diet

Researchers link seizure resistance to a protein that modifies cellular metabolism in the brain. The findings, which shed light on the extremely low-carb ketogenic diet, may lead to the development of new treatments for epilepsy. ScienceDaily: Reverse engineering epilepsy’s ‘miracle’ diet Researchers at Dana-Farber Cancer Institute and Harvard Medical School have proposed an answer, linking resistance […]

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High Fat/Low Carb Diet Could Combat Schizophrenia

Associate Professor Zoltan Sarnyai and his research group from JCU’s Australian Institute of Tropical Health and Medicine (AITHM) have discovered that feeding mice a ketogenic diet, which is high on fat but very low on carbohydrates (sugars), leads to fewer animal behaviours that resemble schizophrenia. ScienceDaily: High fat/low carb diet could combat schizophrenia The ketogenic diet […]

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Fueling the Alzheimer’s Brain

In Alzheimer’s disease (AD), there are early significant deficits in glucose utilization that become increasingly severe as disease progresses. Clinical Neurology News: Fueling the Alzheimer’s brain with fat Most reports from early-onset AD animal models find that these energy deficits are largely due to defects in mitochondrial complex IV and V, and possibly related to mitochondrial fusion and fission […]

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Too Much Sugar Could Increase Depression Risk in Men

Men who consume a lot of added sugar in drinks, cakes and confectionery run an increased risk of depression, according to a new study. The Guardian: Too much sugar could increase depression risk in men, study suggests Researchers from University College London (UCL) looked at sugar in the diet and common mental health problems in a […]

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Ketogenic Diets for Psychiatric Disorders

If you have a brain, you need to know about ketogenic diets. The fact that these specially-formulated low-carbohydrate diets have the power to stop seizures in their tracks is concrete evidence that food has a tremendous impact on brain chemistry and should inspire curiosity about how they work. I first became interested in ketogenic diets as […]

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