Ketogenic diet as a metabolic therapy for mood disorders: Evidence and developments

Despite significant advances in pharmacological and non-pharmacological treatments, mood disorders remain a significant source of mental capital loss, with high rates of treatment resistance, requiring a coordinated effort in investigation and development of efficient, tolerable and accessible novel interventions. Ketogenic diet (KD) is a low-carb diet that substantially changes the energetic matrix of the body […]

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The ketogenic diet as a potential treatment and prevention strategy for Alzheimer’s disease

The prevalence of Alzheimer’s disease, a chronic neurodegenerative condition, is increasing as is the need for effective treatments and preventions. The underlying pathology of Alzheimer’s is not yet fully understood, so existing research has focused on understanding the prominent features of the disease. These include amyloid plaques, which accumulate in the brains of those with […]

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Deaths Attributable to Diabetes in the United States: Comparison of Data Sources and Estimation Approaches

We estimated population attributable fractions (PAF) for cohorts aged 30–84 who were surveyed in the National Health Interview Survey (NHIS) between 1997 and 2009 (N = 282,322) and in the National Health and Nutrition Examination Survey (NHANES) between 1999 and 2010 (N = 21,814). Cohort members were followed prospectively for mortality through 2011. We identified […]

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A Ketogenic Diet Improves Cognition

Age-related cognitive decline has been linked to a diverse set of neurobiological mechanisms, including bidirectional changes in proteins critical for neuron function. Importantly, these alterations are not uniform across the brain. For example, the hippocampus (HPC) and prefrontal cortex (PFC) show distinct patterns of dysfunction in advanced age. Because higher cognitive functions require large-scale interactions […]

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Sugar’s Sick Secrets

Walk into any grocery store, grab a few packaged products, and flip to the ingredients. You’ll likely spot added sugars  –  lots of them  –  provided you can discern their dizzying array of names: sucrose, dextrose, barley malt, agave nectar, high-fructose corn syrup, treacle, to list just a few. Why is our food saturated with […]

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Dietary carbohydrates: role of quality and quantity in chronic disease

Carbohydrate is the only macronutrient with no established minimum requirement. Although many populations have thrived with carbohydrate as their main source of energy, others have done so with few if any carbohydrate containing foods throughout much of the year (eg, traditional diets of the Inuit, Laplanders, and some Native Americans). If carbohydrate is not necessary […]

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Diabetes is linked with cognitive dysfunction

Middle-aged adults with diabetes performed worse on assessments of executive function, attention and memory when compared with adults without diabetes, independent of other cardiovascular risk factors and depression status, according to findings from a population-based study. “Recently, attention has been given to modifiable risk factors to help curtail the increasing prevalence of dementia, and several […]

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Dr. David Perlmutter on the Link Between Sugar and Alzheimer’s Disease

As noted by Perlmutter, even though there’s no conventional treatment for Alzheimer’s, research shows this devastating degenerative neurological disease can be effectively prevented by lowering sugar exposure, increasing exercise and improving the quality of your sleep. “The science is now completely lined up behind us, showing that our dietary choices are having a huge influence on the […]

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Extra-Virgin Olive Oil Preserves Memory and Protects Brain Against Alzheimer’s

The Mediterranean diet, rich in plant-based foods, is associated with a variety of health benefits, including a lower incidence of dementia. Now, researchers at the Lewis Katz School of Medicine at Temple University (LKSOM) have identified a specific ingredient that protects against cognitive decline: extra-virgin olive oil, a major component of the Mediterranean diet. In […]

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