Fructose and Cardiometabolic Health

Recent attention has focused on fructose as having a unique role in the pathogenesis of cardiometabolic diseases. However, because we rarely consume fructose in isolation, the major source of fructose in the diet comes from fructose-containing sugars, sucrose and high fructose corn syrup, in sugar-sweetened beverages and foods. Intake of sugar-sweetened beverages has been consistently […]

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Dietary Restriction Increases Lifespan

Mitochondrial network remodeling between fused and fragmented states facilitates mitophagy, interaction with other organelles, and metabolic flexibility. Aging is associated with a loss of mitochondrial network homeostasis, but cellular processes causally linking these changes to organismal senescence remain unclear. Here, we show that AMP-activated protein kinase (AMPK) and dietary restriction (DR) promote longevity in C. elegans via maintaining […]

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Distinct Circadian Signatures in Liver and Gut Clocks Revealed by Ketogenic Diet

• KD induces tissue-specific reprogramming of the circadian clock in liver and gut • KD induces an increase in liver BMAL1 chromatin recruitment and amplitude of CCGs • KD drives tissue-specific oscillation of PPARα and its target genes • Oscillation of βOHB in gut and serum parallels gut-specific cycling of H3 acetylation The circadian clock […]

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Mitochondria: The Ketogenic Diet—A Metabolism-Based Therapy

Mitochondria are the energy-producing organelles of the cell, generating ATP via oxidative phosphorylation mainly by using pyruvate derived from glycolytic processing of glucose. Ketone bodies generated by fatty acid oxidation can serve as alternative metabolites for aerobic energy production. The ketogenic diet, which is high in fat and low in carbohydrates, mimics the metabolic state […]

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What Will Happen to Your Body If You Walk Every Day

Walking is a totally free, easy exercise that requires little effort, and benefits not only your physical but also your mental well-being. If you’re looking for a simple yet very effective way of losing weight and improving your overall health, walking is something just for you. People who are physically active throughout their life are […]

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Low fat foods contain up to 5 TIMES more sugar of regular versions

Low-fat foods contain up to five times more sugar than their regular equivalents, a Sunday Mirror investigation has found. Companies market lower fat versions as healthier but add sugar to make up for the lack of taste, say experts. Batchelors Super Noodles Chicken has 1.1g of sugar per 100g but its “low fat” variety contains […]

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Management of Type 1 Diabetes With a Very Low–Carbohydrate Diet

New research findings published in the journal PEDIATRICS reveal the power of a very low carb diet to normalize blood sugars for t1 diabetics of all ages with no negative consequences  The study evaluated glycemic control among children and adults with type 1 diabetes mellitus (T1DM) who consume a very low–carbohydrate diet (VLCD). The authors conducted […]

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Cut the Carbs to Avoid Disease

The average Australian diet has been turned on its head by leading nutrition experts. Researchers from CSIRO Health and Biosecurity are urging Aussies to ditch the “low fat” mindset and instead boost intake of healthy fats and protein. And they say reducing carbohydrates is the evidence-based way to help ward off — and even reverse — type […]

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