Beneficial Macrophage Functions in Atherosclerosis and Obesity-Induced Insulin Resistance

The discovery that obesity promotes macrophage accumulation in visceral fat led to the emergence of a new field of inquiry termed “immunometabolism”. This broad field of study was founded on the premise that inflammation and the corresponding increase in macrophage number and activity was a pathologic feature of metabolic diseases. There is abundant data in […]

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Cannabidiol Regulation of Learned Fear

Anxiety and trauma-related disorders are psychiatric diseases with a lifetime prevalence of up to 25%. Phobias and post-traumatic stress disorder (PTSD) are characterized by abnormal and persistent memories of fear-related contexts and cues. The effects of psychological treatments such as exposure therapy are often only temporary and medications can be ineffective and have adverse side […]

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Egg Consumption and Coronary Heart Disease

Objective is to investigate and quantify the potential dose-response association between egg consumption and risk of coronary heart disease and stroke. BMJ: Egg consumption and risk of coronary heart disease and stroke: dose-response meta-analysis of prospective cohort studies Data sources PubMed and Embase prior to June 2012 and references of relevant original papers and review […]

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Sugar, Meat, and Fat Intake, and Non-Dietary Risk Factors for colon cancer

To investigate the relation of dietary intakes of sucrose, meat, and fat, and anthropometric, lifestyle, hormonal, and reproductive factors to colon cancer incidence, data were analyzed from a prospective cohort study of 35,215 Iowa (United States) women, aged 55–69 years and without a history of cancer, who completed mailed dietary and other questionnaires in 1986. […]

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Alzheimer’s Disease Found To Be a Diabetic Disorder Of the Brain

Researchers at Tohoku University have found a promising treatment for Alzheimer’s disease, by noticing a similarity in the way insulin signaling works in the brain and in the pancreas of diabetic patients. Science Daily: Alzheimer’s disease found to be a diabetic disorder of the brain   “In the pancreas, the Kir6.2 channel blockade increases the insulin […]

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Sweetened Drinks and Childhood Obesity

The rising prevalence of obesity in children has been linked in part to the consumption of sugar-sweetened drinks. Our aim was to examine this relation. ScienceDirect: Relation between consumption of sugar-sweetened drinks and childhood obesity: a prospective, observational analysis Methods We enrolled 548 ethnically diverse schoolchildren (age 11·7 years, SD 0·8) from public schools in […]

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Adverse Metabolic Effects of Dietary Fructose

The effects of dietary sugar on risk factors and the processes associated with metabolic disease remain a controversial topic, with recent reviews of the available evidence arriving at widely discrepant conclusions. Publimed: Adverse metabolic effects of dietary fructose: results from the recent epidemiological, clinical, and mechanistic studies. RECENT FINDINGS: There are many recently published epidemiological […]

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Diabetes and Oral Health Problems

The more severe form of gum disease is called periodontitis. When you reach this stage, your gums begin to pull away from your teeth. Pockets form between your teeth and gums. These fill with germs and pus, and deepen. When this happens, you may need gum surgery to save your teeth. If nothing is done, […]

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Low-Fat Dietary Pattern and Weight Change Over 7 Years

Obesity in the United States has increased dramatically during the past several decades. There is debate about optimum calorie balance for prevention of weight gain, and proponents of some low-carbohydrate diet regimens have suggested that the increasing obesity may be attributed, in part, to low-fat, high-carbohydrate diets. Publimed: Low-fat dietary pattern and weight change over […]

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Diabetes & Alzheimer’s — save your brain by going to the gym | Ewan McNay | TEDxAlbany

This talk was given at a local TEDx event, produced independently of the TED Conferences. Recent discoveries (many in my lab) on the links between type 2 diabetes and Alzheimer’s disease; translation of that lab work into real-life advice and consequences. My work examines the role of metabolic processes in regulating brain function, and specifically […]

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