04:03 The Calories notion is false. 13:54 We have a mechanism in our body that determines how fat we get. 19:39 Your body weight set point is being reset upward. 20:23 To reset your body weight set point, you need to get your insulin low for a significant amount of time in order to get your leptin levels low. 24:14 When you eat all day, you are telling your body to store fat all day and you get fat. 25:07 Fat storage is a hormonal signal, not a caloric signal. 29:41 Intermittent fasting is not about how many calories you eat. It is about the time that you are not eating. 31:24 Insulin inhibits lipolysis, stopping you from burning fat. 32:24 On a 7 day water only fast, your insulin falls and you switch from burning food to burning fat. 33:13 During fasting, as your insulin falls, you get a counter-regulatory hormone surge, increasing adrenaline, noradrenaline, growth hormone and cortisol. 33:53 There is a period of gluconeogenesis at around 24 hours into fasting. You will burn protein, not muscle. 35:40 If the old protein is never broken down, you cannot build new protein. 37:26 You get much better retention of lean mass with an intermittent fasting strategy over cutting calories. 38:24 Biggest Loser style diets sink metabolic rates. 42:15 Women can fast. Ghrelin is the hunger hormone. Women have higher ghrelin spikes. 43:01 If you don’t eat over 24 hours ghrelin spikes 3 times, at breakfast, lunch and dinner, then drops. Hunger does not continue to increase. 45:04 Cravings disappear with fasting and keto. 49:38 You can eat high carb foods and keep low insulin. 51:09 Sugar is more fattening than other carbohydrates. 53:51 Natural foods have natural satiety mechanisms. 01:08:31 Type 2 diabetes is misunderstood by doctors. 01:10:08 Blood glucose is a symptom of type 2 diabetes. We treat the symptom, not the disease. 01:12:15 Type 2 diabetes is reversible, except for the very late stage. 01:16:42 The longer you’ve been overweight the more it effects weight loss. 01:18:08 There are conflicts of interest in medicine. Much evidence is produced by pharmaceutical companies. Universities take funding from industry and produce shoddy research. 01:30:21 Bias in nutrition science is rampant and has stymied the advancement of actual science. Special interest needs to be out of research.