Timing of food intake is more potent than habitual voluntary exercise to prevent diet-induced obesity in mice

Inappropriate eating habits such as eating late at night are associated with risk for abnormal weight-gain and adiposity. We previously reported that time-imposed feeding during the daytime (inactive phase) induces obesity and metabolic disorders accompanied by physical inactivity in mice. The present study compares metabolic changes induced in mice by time-imposed feeding under voluntary wheel-running […]

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Genetic Susceptibility for Childhood BMI has no Impact on Weight Loss Following Lifestyle Intervention

This study aimed to investigate the effect of a genetic risk score (GRS) comprising 15 single‐nucleotide polymorphisms, previously shown to associate with childhood BMI, on the baseline cardiometabolic traits and the response to a lifestyle intervention in Danish children and adolescents. Methods Children and adolescents with overweight or obesity (n = 920) and a population‐based control sample […]

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Sitting Is The New Smoking

An alien visitor to our planet would be perplexed by modern human life, not least our relationship with physical exertion. After 6 million years of hunter-gatherer existence, humans can be observed sheltering in warm rooms, counteracting the tiresome effects of earth’s gravity by slouching on comfortable seats in front of glowing screens, being whisked effortlessly […]

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Exercise for cognitive brain health in aging

We systematically appraised randomized controlled trials proposing exercise to influence cognition in older adults to (1) assess the methodologic quality using Cochrane criteria; (2) describe various exercise dose measures and assess their relationship with improved cognitive performance; and (3) identify consistent patterns of reported effects on cognition. There was overall good methodologic quality in all […]

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Why The Keto Diet Will Change Your Life | Mark Sisson on Health Theory

Mark Sisson is a former endurance athlete turned nutrition author and entrepreneur. In 2006, he began his popular health blog, Mark’s Daily Apple, where he’s blogged every day for 12+ years. Mark is the founder of Primal Kitchen Foods and best-selling author of several books including The Primal Blueprint and his most recent hit, The […]

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Walk After Meals Is More Effective for Lowering Postprandial Glycaemia in Type 2 Diabetes

Regular physical activity is a cornerstone of diabetes management. We conducted a study to evaluate whether specifying the timing of walking in relation to meals enhances the benefits conferred by current physical activity guidelines. A total of 41 adults with type 2 diabetes mellitus (mean ± SD age 60 ± 9.9 years; mean diabetes duration 10 years) participated in this randomised, […]

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Exercise Training Improves the Insulin Sensitivity

It is not known whether the beneficial effects of exercise training on insulin sensitivity are due to changes in hepatic and peripheral insulin sensitivity or whether the changes in insulin sensitivity can be explained by adaptive changes in fatty acid metabolism, changes in visceral fat or changes in liver and muscle triacylglycerol content. We investigated […]

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The Battle of the Diets: Is Anyone Winning (At Losing?)

The case for low-carbohydrate diets is gaining weight. Christopher Gardner, PhD, assistant professor of medicine at the Stanford Prevention Research Center, has completed the largest and longest-ever comparison of four popular diets using real-world conditions, which he discusses – the lowest-carbohydrate Atkins diet came out on top.

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