Comparison of a Low-Fat Diet to a Low-Carbohydrate Diet on Weight Loss, Body Composition, and Risk Factors for Diabetes and Cardiovascular Disease

Overweight and obese men and women (24-61 yr of age) were recruited into a randomized trial to compare the effects of a low-fat (LF) vs. a low-carbohydrate (LC) diet on weight loss. Publimed: Comparison of a low-fat diet to a low-carbohydrate diet on weight loss, body composition, and risk factors for diabetes and cardiovascular disease in […]

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Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet

We recently proposed that the biological markers improved by carbohydrate restriction were precisely those that define the metabolic syndrome (MetS), and that the common thread was regulation of insulin as a control element. Springer Link: Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet We specifically tested the […]

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Comparison of Energy-Restricted Very Low-Carbohydrate and Low-Fat Diets on Weight Loss and Body Composition

The objective is to compare the effects of isocaloric, energy-restricted very low-carbohydrate ketogenic (VLCK) and low-fat (LF) diets on weight loss, body composition, trunk fat mass, and resting energy expenditure (REE) in overweight/obese men and women. Design Randomized, balanced, two diet period clinical intervention study. Subjects were prescribed two energy-restricted (-500 kcal/day) diets: a VLCK […]

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Efficacy and Safety of a High Protein, Low Carbohydrate Diet for Weight Loss in Severely Obese Adolescents

46 individuals were randomized to a low-carb or a low-fat diet for 36 weeks. Low-fat group was calorie restricted. Weight Loss: The low-carb group lost more weight and had greater decreases in BMI than the low-fat group. Conclusion: The low-carb group had greater reductions in BMI. Various biomarkers improved in both groups, but there was no significant […]

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Long-Term Effects of A Very-Low-Carbohydrate Weight Loss Diet Compared with A Low-Fat Diet

Long-term weight loss and cardiometabolic effects of a very-low-carbohydrate, high-saturated-fat diet (LC) and a high-carbohydrate, low-fat diet (LF) have not been evaluated under isocaloric conditions. 118 individuals with abdominal obesity were randomized to a low-carb or a low-fat diet for 1 year. Both diets were calorie restricted. Weight Loss: The low-carb group lost 14.5 kg (32 […]

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Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet

We recently proposed that the biological markers improved by carbohydrate restriction were precisely those that define the metabolic syndrome (MetS), and that the common thread was regulation of insulin as a control element. We specifically tested the idea with a 12-week study comparing two hypocaloric diets (~1,500 kcal): a carbohydrate-restricted diet (CRD) (%carbohydrate:fat:protein = 12:59:28) and a low-fat […]

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Metabolic Effects of Weight Loss on a Very-Low-Carbohydrate Diet Compared With an Isocaloric High-Carbohydrate Diet in Abdominally Obese Subjects

This study was designed to compare the effects of an energy-reduced, isocaloric very-low-carbohydrate, high-fat (VLCHF) diet and a high-carbohydrate, low-fat (HCLF) diet on weight loss and cardiovascular disease (CVD) risk outcomes. 88 individuals with abdominal obesity were randomized to a very low-carb or a low-fat diet for 24 weeks. Both diets were calorie restricted. Weight […]

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A Low-Carbohydrate Diet is More Effective in Reducing Body Weight than Healthy Eating

13 diabetic and 13 non-diabetic individuals were randomized to a low-carb diet or a “healthy eating” diet that followed the Diabetes UK recommendations (a calorie restricted, low-fat diet). Study went on for 3 months. Weight Loss: The low-carb group lost 6.9 kg (15.2 lbs), compared to 2.1 kg (4.6 lbs) in the low-fat group. Conclusion: The low-carb […]

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Intake of Saturated and Trans Unsaturated Fatty Acids and Risk of All Cause Mortality, Cardiovascular Disease, and Type 2 Diabetes

This systematic review and meta-analysis reviewed observational studies on the association of saturated fat and heart disease, stroke, type 2 diabetes and death from cardiovascular disease. The data included 73 studies, with 90,500–339,000 participants for each endpoint. Results: Saturated fat intake was not linked with heart disease, stroke, type 2 diabetes or dying of any cause. […]

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Fasting Plasma Glucose and Insulin Are Determinants of Dietary Weight Loss Success

Researchers from the University of Copenhagen, together with colleagues from the University of Colorado, Tufts University, Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBER OBN) and Gelesis, Inc., presented new data demonstrating that blood sugar (glucose) and/or fasting insulin should be used to select the right diet, particularly for […]

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