Man loses over 300 pounds on a low-carb diet

Tony has lost an impressive 326 lbs (148 kg) following a low-carb high-protein diet and walking. Congratulations! His weight-loss journey started in May 2016 after the wildfire in Fort McMurray. At this time, he had to use two airplane seats during the evacuation, delaying other people from getting to safety. This increased his motivation to attempt a […]

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Distinct Circadian Signatures in Liver and Gut Clocks Revealed by Ketogenic Diet

KD induces tissue-specific reprogramming of the circadian clock in liver and gut KD induces an increase in liver BMAL1 chromatin recruitment and amplitude of CCGs KD drives tissue-specific oscillation of PPARα and its target genes Oscillation of βOHB in gut and serum parallels gut-specific cycling of H3 acetylation   The circadian clock orchestrates rhythms in […]

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Supra-Additive Effects of Combining Fat and Carbohydrate on Food Reward

Fat and carbohydrate interact to potentiate reward independently of liking This is reflected in supra-additive responses in the striatum during food valuation Participants are able to estimate energy density from fat, but not carbohydrate Accurate estimation of energy density recruits a prefrontal-fusiform gyrus circuit Post-ingestive signals conveying information about the nutritive properties of food are […]

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Obesity is common, serious and costly

The prevalence of obesity was 39.8% and affected about 93.3 million of U.S. adults in 2015-2016. [Read CDC National Center for Health Statistics (NCHS) data brief PDF-603KB] Obesity-related conditions include heart disease, stroke, type 2 diabetes and certain types of cancer, some of the leading causes of preventable death. [Read guidelines] The estimated annual medical cost […]

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Continuous Remote Care Model Utilizing Nutritional Ketosis Improves Type 2 Diabetes Risk Factors in Patients with Prediabetes

Prediabetes (preT2D) is a major U.S. public health concern, as over 84 million adults are at greater risk of cardiovascular disease and progression to type 2 diabetes (T2D). Abnormal glucose, BMI, blood pressure, and blood lipids are risk factors for progression to T2D. The purpose of this single-arm prospective longitudinal investigation was to assess change […]

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Dr. Maryanne Demasi – ‘Statin Wars: Have we been misled by the evidence?’

Dr. Maryanne Demasi is a former medical scientist who completed her PhD in Medicine at the University of Adelaide. Her research focused on the pathology of Rheumatoid arthritis and potential therapies. Her innovative research has appeared in several internationally published medical journals. Leaving her lab coat behind, Maryanne accepted a position as a political advisor […]

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Reverse and Prevent Diabetes with Dr. Brian Mowll

Type 2 Diabetes and pre-diabetes is a real threat for emotional eaters. But it can be reversed. Dr. Brian Mowll is the founder and medical director of SweetLife® Diabetes Health Centers. He coaches clients worldwide by showing them how optimize their health and metabolism, control blood sugar, and reverse type 2 diabetes using a natural, […]

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Carbohydrate restriction has a more favorable impact on the metabolic syndrome than a low fat diet

We recently proposed that the biological markers improved by carbohydrate restriction were precisely those that define the metabolic syndrome (MetS), and that the common thread was regulation of insulin as a control element. We specifically tested the idea with a 12-week study comparing two hypocaloric diets (approximately 1,500 kcal): a carbohydrate-restricted diet (CRD) (%carbohydrate:fat:protein = […]

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Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets

Very-low-carbohydrate diets or ketogenic diets have been in use since the 1920s as a therapy for epilepsy and can, in some cases, completely remove the need for medication. From the 1960s onwards they have become widely known as one of the most common methods for obesity treatment. Recent work over the last decade or so […]

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Why The Keto Diet Will Change Your Life | Mark Sisson on Health Theory

Mark Sisson is a former endurance athlete turned nutrition author and entrepreneur. In 2006, he began his popular health blog, Mark’s Daily Apple, where he’s blogged every day for 12+ years. Mark is the founder of Primal Kitchen Foods and best-selling author of several books including The Primal Blueprint and his most recent hit, The […]

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