Increasing Adiposity – Consequence or Cause of Overeating?

Ninety years ago, an editorial in JAMA questioned the prevailing approach to obesity treatment: “When we read that ‘the fat woman has the remedy in her own hands—or rather between her own teeth’ . . . there is an implication that obesity is usually merely the result of unsatisfactory dietary bookkeeping. . . [Although logic suggests that […]

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Circadian Hormonal Inputs to Regulate Fat Cell Differentiation

Circadian adipogenic stimuli are rejected by the adipocyte differentiation system This circadian filtering requires fast and slow positive feedback to PPARG Loss of circadian glucocorticoid oscillations in mice increases fat mass Glucocorticoid and other adipogenic hormones are secreted in mammals in circadian oscillations. Loss of this circadian oscillation pattern correlates with obesity in humans, raising […]

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Exercising to Relax

How does exercise reduce stress, and can exercise really be relaxing? Rest and relaxation. It’s such a common expression that it has become a cliche. And although rest really can be relaxing, the pat phrase causes many men to overlook the fact that exercise can also be relaxing. It’s true for most forms of physical […]

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Fructose and Insulin Sensitivity in Patients with Type 2 Diabetes

The effect of dietary fructose (20% of carbohydrate calories, 45–65 g day−1 for 4 weeks) on glycaemic control, serum lipid, lipoprotein and apoprotein A‐I and A‐II concentrations and on insulin sensitivity was studied in 10 type 2 diabetic patients. The study was done in a randomized, double‐blind fashion with crystalline fructose or placebo administered evenly during […]

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Effects of Sugar on Blood Pressure and Lipids

Sugar has been suggested as a central risk factor in the development of noncommunicable diseases. We assessed the evidence of the effects of free sugars compared with complex carbohydrates on selected cardiovascular disease risk factors. DWe conducted a systematic review and meta-analysis of intervention trials to compare diets that provide a given amount of energy […]

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What is a correct food portion?

Nutrition scientists have devised a new way of measuring out food portions – using your hands, thumbs and fists rather than a set of scales. The new guide from the British Nutrition Foundation has been created after studying portion sizes around the world and what is available in UK supermarkets. It is thought that better portion control […]

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Implementing a Low-Carbohydrate, Ketogenic Diet to Manage Type 2 Diabetes Mellitus.

Type 2 diabetes mellitus (T2DM) has reached epidemic proportions in the modern world. For individuals affected by obesity-related T2DM, clinical studies have shown that carbohydrate restriction and weight loss can improve hyperglycemia, obesity, and T2DM. Reducing carbohydrate intake to a certain level, typically below 50 g per day, leads to increased ketogenesis in order to provide fuel for […]

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Average 10-year-old has eaten 18 years’ worth of sugar

The average 10-year-old has consumed as much sugar in their lifetime as the recommended limit for an 18-year-old, according to Public Health England (PHE), which is warning of serious implications for obesity and health. Children are consuming the equivalent of eight excess sugar cubes a day, or 2,800 a year, says PHE, which has launched a new […]

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