Dietary Glycemic Index and Load and the Risk of Type 2 Diabetes

Published meta-analyses indicate significant but inconsistent incident type-2 diabetes (T2D)-dietary glycemic index (GI) and glycemic load (GL) risk ratios or risk relations (RR). It is now over a decade ago that a published meta-analysis used a predefined standard to identify valid studies. Considering valid studies only, and using random effects dose–response meta-analysis (DRM) while withdrawing […]

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The Carbohydrate-Insulin Model of Obesity

Despite intensive research, the causes of the obesity epidemic remain incompletely understood and conventional calorie-restricted diets continue to lack long-term efficacy. According to the carbohydrate-insulin model (CIM) of obesity, recent increases in the consumption of processed, high–glycemic-load carbohydrates produce hormonal changes that promote calorie deposition in adipose tissue, exacerbate hunger, and lower energy expenditure. Basic […]

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Fructose as A Key Player in the Development of Fatty Liver Disease

We aimed to investigate whether increased consumption of fructose is linked to the increased prevalence of fatty liver. The prevalence of nonalcoholic steatohepatitis (NASH) is 3% and 20% in nonobese and obese subjects, respectively. Obesity is a low-grade chronic inflammatory condition and obesity-related cytokines such as interleukin-6, adiponectin, leptin, and tumor necrosis factor-α may play […]

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Fasting and Its Impact on Skin Anatomy, Physiology, and Physiopathology

Skin serves as the first protective line and barrier of the body. Like many other organs, skin can be affected by several disorders in response to external factors such as pathogens, ultraviolet light, and pollution, as well as endogenous alterations related to aging and/or oxidative stress disturbance. Researchers have reported new insights into how skin […]

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38 % Increased Risk of Type 2 Diabetes Associated to Statins

There are several epidemiological studies on the association between statins and incident diabetes, but most of them lack details. In this study, we aimed to investigate the association of statin use with glycaemic traits and incident type 2 diabetes. Using the prospective population‐based Rotterdam Study, we included 9535 individuals free from diabetes at baseline (>45 […]

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Fighting Fat With Fat | Nick Murphy

Think about this, what kind of pressure are we exerting on our health each and every day? What is the effect of the food choices we make… or don’t make? Nick Murphy, owner of Mission Fitness, is a Certified Personal Trainer and Life Coach. He has 20+ years of experience in his field and is […]

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Impact of Sleep on Appetite Regulation

Sleep duration seems to play an important role in the regulation of human leptin and ghrelin levels, hunger and appetite. Differences in energy balance between sleep restriction and sleep extension do not entirely explain the differences in appetite regulation since the laboratory studies kept energy intake and activity levels constant for both bedtime conditions.Sleep loss […]

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Dr. Sheila Cook – ‘Back to the Future: A low carbohydrate diet in Type 1 Diabetes’

Dr Sheila Cook is the Director of Diabetes and Endocrinology at Toowoomba Hospital, and Deputy Director of Clinical Training at the University of Queensland Rural Clinical School, Toowoomba. She completed her specialist endocrine and obstetric medicine training in Brisbane and since arriving at Toowoomba Hospital in 2006, she has established the Diabetes in Pregnancy Clinic, […]

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Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

Studies in animals have documented that, compared with glucose, dietary fructose induces dyslipidemia and insulin resistance. To assess the relative effects of these dietary sugars during sustained consumption in humans, overweight and obese subjects consumed glucose- or fructose-sweetened beverages providing 25% of energy requirements for 10 weeks. Although both groups exhibited similar weight gain during […]

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