The Low-Carbohydrate Diet and Cardiovascular Risk Factors

Obesity is an important public health issue because of its high prevalence and concomitant increase in risk of cardiovascular diseases. PMC: The low-carbohydrate diet and cardiovascular risk factors: Evidence from epidemiologic studies Low carbohydrate diets are popular for weight loss and weight management but are not recommended in leading guidelines due to the perception that increases […]

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Isocaloric Fructose Restriction and Metabolic Improvement in Obese Children

Dietary fructose is implicated in metabolic syndrome, but intervention studies are confounded by positive caloric balance, changes in adiposity, or artifactually high amounts. This study determined whether isocaloric substitution of starch for sugar would improve metabolic parameters in Latino (n = 27) and African-American (n = 16) children with obesity and metabolic syndrome. Wiley Online Library: Isocaloric fructose restriction and […]

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The Cholesterol and Calorie Hypotheses Are Both Dead

Emerging evidence shows that insulin resistance is the most important predictor of cardiovascular disease and type 2 diabetes. The Pharmaceutical Journal: The cholesterol and calorie hypotheses are both dead — it is time to focus on the real culprit: insulin resistance Aggressive lowering of low-density lipoprotein cholesterol (LDL-C) has been the cornerstone of preventative cardiology for decades. Statins […]

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To our knowledge, the effect of magnesium supplementation on blood pressure (BP) in individuals with preclinical or noncommunicable diseases has not been previously investigated in a meta-analysis, and the findings from randomized controlled trials (RCTs) have been inconsistent. The American Journal of Clinical Nutrition: The effect of magnesium supplementation on blood pressure in individuals with insulin […]

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Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet

We recently proposed that the biological markers improved by carbohydrate restriction were precisely those that define the metabolic syndrome (MetS), and that the common thread was regulation of insulin as a control element. Springer Link: Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet We specifically tested the […]

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Association of Dietary, Circulating, and Supplement Fatty Acids with Coronary Risk

This study reviewed cohort studies and randomized controlled trials on the link between fatty acids and the risk of heart disease or sudden cardiac death. The study included 49 observational studies with more than 550,000 participants, as well as 27 randomized controlled trials with more than 100,000 participants. Results: The study did not find any link […]

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Meta-Analysis of Prospective Cohort Studies Evaluating the Association of Saturated Fat with Cardiovascular Disease

This meta-analysis reviewed evidence from observational studies on the link between dietary saturated fat and risk of heart disease and stroke. The studies included a total of 347,747 participants, who were followed for 5–23 years. Results: During follow up, about 3% of participants (11,006 people) developed heart disease or stroke. Saturated fat intake was not linked […]

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Intake of Saturated and Trans Unsaturated Fatty Acids and Risk of All Cause Mortality, Cardiovascular Disease, and Type 2 Diabetes

This systematic review and meta-analysis reviewed observational studies on the association of saturated fat and heart disease, stroke, type 2 diabetes and death from cardiovascular disease. The data included 73 studies, with 90,500–339,000 participants for each endpoint. Results: Saturated fat intake was not linked with heart disease, stroke, type 2 diabetes or dying of any cause. […]

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The National Cholesterol Education Program Diet (Low Fat) vs A Diet Lower in Carbohydrates and Higher in Protein and Monounsaturated Fat (Low Carb)

Details: 60 overweight individuals were randomized to a low-carb diet high in monounsaturated fat, or a low-fat diet based on the National Cholesterol Education Program (NCEP). Both groups were calorie restricted and the study went on for 12 weeks. Weight Loss: The low-carb group lost an average of 6.2 kg (13.6 lbs), while the low-fat […]

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