The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus

Dietary carbohydrate is the major determinant of postprandial glucose levels, and several clinical studies have shown that low-carbohydrate diets improve glycemic control. In this study, we tested the hypothesis that a diet lower in carbohydrate would lead to greater improvement in glycemic control over a 24-week period in patients with obesity and type 2 diabetes […]

Read More »

Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets

Very-low-carbohydrate diets or ketogenic diets have been in use since the 1920s as a therapy for epilepsy and can, in some cases, completely remove the need for medication. From the 1960s onwards they have become widely known as one of the most common methods for obesity treatment. Recent work over the last decade or so […]

Read More »

Long-term effects of a ketogenic diet in obese patients

Although various studies have examined the short-term effects of a ketogenic diet in reducing weight in obese patients, its long-term effects on various physical and biochemical parameters are not known. To determine the effects of a 24-week ketogenic diet (consisting of 30 g carbohydrate, 1 g/kg body weight protein, 20% saturated fat, and 80% polyunsaturated […]

Read More »

Twelve-Month Outcomes of A Randomized Trial of A Moderate-Carbohydrate Versus Very Low-Carbohydrate Diet in Overweight Adults with Type 2 Diabetes Mellitus or Prediabetes

Dietary treatment is important in management of type 2 diabetes or prediabetes, but uncertainty exists about the optimal diet. We randomized adults (n = 34) with glycated hemoglobin (HbA1c) > 6.0% and elevated body weight (BMI > 25) to a very low-carbohydrate ketogenic (LCK) diet (n = 16) or a moderate-carbohydrate, calorie-restricted, low-fat (MCCR) diet (n = 18). All participants were encouraged to be physically […]

Read More »

Robert Lustig, MD, What is Metabolic Syndrome, and Why are Children Getting It?

A grouping of health conditions associated with an increased risk for heart disease and type 2 diabetes. Conditions include hypertension, a large waist, high triglyceride levels, low HDL cholesterol levels, and above-normal blood glucose levels.

Read More »

A Link Between the Digestive System and Problems with Sleep

When we lie awake at night, unable to sleep, we usually blame stress, depression, anxiety, adrenaline or the memory of something stupid we said in 2003. But what if our guts were actually the culprit? What if the trillions of microbes sitting in our small intestines – known collectively as the microbiome or microbiota – […]

Read More »

Associations between Adipokines and Obesity-Related Cancer

The majority of breast cancers require action of oestrogens for their growth and progression. In addition, leptin in excess may also contribute to the pathogenesis of breast cancer. Vona-Davies and Rose summarises the contradictory results found in case-control studies (one of which was nested within a prospective study), with 3/10 showing positive correlations (55). More […]

Read More »

Carbohydrates Are Killing Us

This year, more than 610,000 Americans will die from heart disease. It’s the leading cause of death for both men and women. For decades, doctors and nutritionists prescribed low-fat diets to people trying to lower their risk of heart disease. Saturated fats in meats and dairy products were thought to clog our arteries. Grains — […]

Read More »

Not getting enough sleep seems to be even more deadly than we thought, new studies show

A trio of new studies show that too little or too much sleep is associated with an increased risk for cardiovascular disease.  Sleeping less than five hours per night raises the risk for a heart attack or stroke by about the same degree as smoking does, according one study in older men. This adds to a significant body of evidence that […]

Read More »