All The Ways You’re Sabotaging Your Health by Overdoing It On Sugar

Sugar lurks in dozens of unsuspecting foods, from yogurts and salad dressings to juices and sauces. Even when sucrose — the popular form of table sugar is not present in a food item, sugar’s cousins fructose and dextrose can likely be found somewhere on the label. To truly avoid sugar, you’d also have to cut out simple carbohydrates, including the ones […]

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The Toll of America’s Obesity

Beyond the human suffering, diet-related diseases impose massive economic costs. Obesity rates in the United States continue to worsen. So, too, does economic inequality. Are these trends related? After remaining essentially flat in the 1950s and 1960s, the prevalence of obesity doubled in adults and tripled in children between the 1970s and 2000. According to new data from the Centers […]

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Carbotoxicity

Modern nutrition is often characterized by the excessive intake of different types of carbohydrates ranging from digestible polysaccharides to refined sugars that collectively mediate noxious effects on human health, a phenomenon that we refer to as “carbotoxicity.” Epidemiological and experimental evidence combined with clinical intervention trials underscore the negative impact of excessive carbohydrate uptake, as […]

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An Update on Glucose Toxicity

Chronic exposure of glucose rich environment creates several physiological and pathophysiological changes. There are several pathways by which hyperglycemia exacerbate its toxic effect on cells, tissues and organ systems. Hyperglycemia can induce oxidative stress, upsurge polyol pathway, activate protein kinase C (PKC), enhance hexosamine biosynthetic pathway (HBP), promote the formation of advanced glycation end-products(AGEs) and finally alters gene expressions. Prolonged hyperglycemic condition leads to severe diabetic condition by […]

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Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets

Very-low-carbohydrate diets or ketogenic diets have been in use since the 1920s as a therapy for epilepsy and can, in some cases, completely remove the need for medication. From the 1960s onwards they have become widely known as one of the most common methods for obesity treatment. Recent work over the last decade or so […]

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Robert Lustig, MD, What is Metabolic Syndrome, and Why are Children Getting It?

A grouping of health conditions associated with an increased risk for heart disease and type 2 diabetes. Conditions include hypertension, a large waist, high triglyceride levels, low HDL cholesterol levels, and above-normal blood glucose levels.

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Juice Is Not Healthy

Obesity affects 40 percent of adults and 19 percent of children in the United States and accounts for more than $168 billion in health care spendingeach year. Sugary beverages are thought to be one of the major drivers of the obesity epidemic. These drinks (think soda and sports drinks) are the largest single source of added sugars for Americans and contribute, on […]

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Distinct Circadian Signatures in Liver and Gut Clocks Revealed by Ketogenic Diet

KD induces tissue-specific reprogramming of the circadian clock in liver and gut KD induces an increase in liver BMAL1 chromatin recruitment and amplitude of CCGs KD drives tissue-specific oscillation of PPARα and its target genes Oscillation of βOHB in gut and serum parallels gut-specific cycling of H3 acetylation   The circadian clock orchestrates rhythms in […]

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Arsenic, Lead Found in Popular Protein Supplements

Clean Label Project™ completed a study of 134 protein powder products from 52 brands. Products were screened for over 130 toxins including heavy metals, BPA, pesticides, and other contaminants with links to cancer and other health conditions. PRODUCTS Clean Label Project had the top-selling protein powder products – animal-based, whey, and plant-based – tested and reviewed […]

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