Prevalence of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population

Prevalence of nonalcoholic fatty liver disease (NAFLD) has not been well established. The purpose of this study was to prospectively define the prevalence of both NAFLD and nonalcoholic steatohepatitis (NASH). Outpatients 18 to 70 years old were recruited from Brooke Army Medical Center. All patients completed a baseline questionnaire and ultrasound. If fatty liver was […]

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Epidemic Growing of Liver Disease among United States adolescents

The objective of teh study is to assess recent trends in nonalcoholic fatty liver disease (NAFLD) prevalence among US adolescents. Cross-sectional data from 12 714 12-19 year olds (exclusions: chronic hepatitis, hepatotoxic medications) in the National Health and Examination Survey between 1988-1994 and 2007-2010 were used to estimate trends in suspected NAFLD, defined as overweight (body […]

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High-sugar diets, type 2 diabetes and Alzheimer’s disease

Recent findings suggest that high-sugar diets can lead to cognitive impairment predisposing to neurodegenerative disorders such as Alzheimer’s disease. This article discusses metabolic derangements induced by high-fructose/sucrose diets and presents evidence for the involvement of insulin resistance in sporadic Alzheimer’s disease pathogenesis. There has been much concern regarding the role of dietary sugars(fructose/sucrose) in the development […]

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FGF21: an endocrine inhibitor of sugar and alcohol appetite.

Fibroblast growth factor 21 (FGF21) is a liver-derived hormone with pleiotropic metabolic effects. Its production is induced by varied dietary imbalances in mice (including low-protein and ketogenic diets, fructose feeding, and ethanol), hinting that it might influence food preference given the role of the liver in maintaining homeostatic levels of circulating nutrients. In 2016, it […]

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Troubleshooting the Ketogenic Diet for Optimal Weight and Health

Dr. Steve Phinney is a physician-scientist who has spent 35 years studying diet, exercise, fatty acids, and inflammation. He has published over 70 papers and several patents. He received his MD from Stanford University, his PhD in Nutritional Biochemistry from MIT, and post-doctoral training at the University of Vermont and Harvard.

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Ketogenic Diet For Cancer, Epilepsy & Diabetes With Dr. Dominic D’Agostino

Is the ketogenic diet for cancer healthy? Does it prevent epilepsy, seizures and diabetes? Dr. Dominic D’Agostino talks about the keto diet for not just preventing cancer but also treating it. The ketogenic diet helps to stop cancer cells from using sugar to grow and even causes apoptosis (cell death) in certain instances. Dr. Dom […]

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Emerging Cancer Trends among Young Adults in the USA

Cancer trends in young adults, often under 50 years, reflect recent changes in carcinogenic exposures, which could foreshadow the future overall disease burden. Previous studies reported an increase in early onset colorectal cancer, which could partly reflect the obesity epidemic. We examined age-specific contemporary incidence trends in the USA for 30 common cancers, including 12 […]

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High-Fructose Corn Syrup Enhances Intestinal Tumor Growth

Excessive consumption of beverages sweetened with high-fructose corn syrup (HFCS) is associated with obesity and with an increased risk of colorectal cancer. Whether HFCS contributes directly to tumorigenesis is unclear. We investigated the effects of daily oral administration of HFCS in adenomatous polyposis coli (APC) mutant mice, which are predisposed to develop intestinal tumors. The […]

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