KetoNutrition: From Science to Application

An impressive body of scientific evidence over the last 15 years documents long term benefits of carbohydrate-restricted, especially ketogenic, diets. We now understand molecular mechanisms and why they work. Popular books and articles now challenge the advice ‘carbohydrates are good and fats are bad.’ Circa mid-19th century urinary ketones were identified in diabetics sealing their […]

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Diabetes and Obesity Still on the Rise

A new report on the continued alarming rise of diabetes in the U.S. illustrates how decades of government dietary guidance has thus far failed to contain this costly and debilitating disease. As part of their State of American Well-Being series, Gallup and Sharecare found that 11.5% of the U.S. adult population was diagnosed with type […]

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Association Between Ultraprocessed Food Consumption and Risk of Mortality

Question  Is high consumption of ultraprocessed food associated with an increase in overall mortality risk? Findings  In this cohort study of 44 551 French adults 45 years or older, a 10% increase in the proportion of ultraprocessed food consumption was statistically significantly associated with a 14% higher risk of all-cause mortality. Meaning  An increase in ultraprocessed food consumption may […]

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Low-carbohydrate diet in type 2 diabetes: stable improvement of bodyweight and glycemic control during 44 months follow-up

Low-carbohydrate diets, due to their potent antihyperglycemic effect, are an intuitively attractive approach to the management of obese patients with type 2 diabetes. We previously reported that a 20% carbohydrate diet was significantly superior to a 55–60% carbohydrate diet with regard to bodyweight and glycemic control in 2 groups of obese diabetes patients observed closely […]

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The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus

Dietary carbohydrate is the major determinant of postprandial glucose levels, and several clinical studies have shown that low-carbohydrate diets improve glycemic control. In this study, we tested the hypothesis that a diet lower in carbohydrate would lead to greater improvement in glycemic control over a 24-week period in patients with obesity and type 2 diabetes […]

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High Blood Sugar Can Cause Heart Disease

Type 2 diabetes can increase the risk of developing heart disease if the blood sugar condition is not controlled properly. If you have diabetes, how can you lower your risk of complications such as heart attacks and strokes? Type 2 diabetes is when the level of sugar in the blood is too high. The condition is lifelong, […]

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Should dietary fat guidelines have been introduced?

Zoë Harcombe was the first pupil from her school to graduate from Cambridge University. While studying maths and economics at this historic institution, Zoë set out to answer the million dollar question – “Why do you overeat? When all you want is to be slim?” This became the title of Zoë’s first book – published […]

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Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain

We investigated whether ultra-processed foods affect energy intake in20 weight-stable adults, aged (mean±SE) 31.2±1.6y and BMI=27±1.5kg/m2. Subjects were admitted to the NIH Clinical Center and randomized to receive either ultra-processed or unprocessed diets for 2 weeks immediately followed by the alternate diet for 2 weeks. Meals were designed to be matched for presented calories, energy […]

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