Sugar versus fat: elimination of glycogen storage improves lipid accumulation

Triacylglycerol (TAG) and glycogen are the two major metabolites for carbon storage in most eukaryotic organisms. We investigated the glycogen metabolism of the oleaginous Yarrowia lipolytica and found that this yeast accumulates up to 16% glycogen in its biomass. Publimed: Sugar versus fat: elimination of glycogen storage improves lipid accumulation  Assuming that elimination of glycogen synthesis […]

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Sugar Consumption Produces Effects Similar to Early Life Stress Exposure

Adverse early life experience is a known risk factor for psychiatric disorders. It is also known that stress influences food preference. Frontiers: Sugar Consumption Produces Effects Similar to Early Life Stress Exposure on Hippocampal Markers of Neurogenesis and Stress Response We were interested in exploring whether the choice of diet following early life stress exerts long-lasting […]

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Excess exposure to insulin is the primary cause of insulin resistance and its associated atherosclerosis.

The main goal of this review is to provide more specific and effective targets for prevention and treatment of insulin resistance and associated atherosclerosis. Publimed: Excess exposure to insulin is the primary cause of insulin resistance and its associated atherosclerosis. Modern technologies and medicine have vastly improved human health and prolonged the average life span of […]

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Remission of Pre-diabetes to Normal Glucose Tolerance

Remission of pre-diabetes to normal is an important health concern which has had little success in the past. This study objective was to determine the effect on remission of pre-diabetes with a high protein (HP) versus high carbohydrate (HC) diet and effects on metabolic parameters, lean and fat body mass in prediabetic, obese subjects after […]

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Ketogenic Diet Combined With Radiation and Chemotherapy for Locally Advanced Lung Cancer and Pancreatic Cancer

Ketogenic diets are low in carbohydrates and high in fat, which forces cells to rely more heavily upon mitochondrial oxidation of fatty acids for energy. Relative to normal cells, cancer cells are believed to exist under a condition of chronic mitochondrial oxidative stress that is compensated for by increases in glucose metabolism to generate reducing […]

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Silicon Valley’s elite are flocking to an extreme high-fat diet in hopes of living longer

Silicon Valley’s investors are trying out ketogenic diets, which involves extreme carb restriction. Some are reporting rapid weight loss and better energy. Side-effects also include crankiness and bad breath. A venture-backed company is hoping to reverse type 2 diabetes with “nutritional ketosis.” CNBC: Silicon Valley’s elite are flocking to an extreme high-fat diet in hopes of […]

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