Neuroinflammation and Psychiatric Illness

Multiple lines of evidence support the pathogenic role of neuroinflammation in psychiatric illness. While systemic autoimmune diseases are well-documented causes of neuropsychiatric disorders, synaptic autoimmune encephalitides with psychotic symptoms often go under-recognized. Parallel to the link between psychiatric symptoms and autoimmunity in autoimmune diseases, neuroimmunological abnormalities occur in classical psychiatric disorders (for example, major depressive, […]

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Prolonged Cannabidiol Treatment Lacks on Detrimental Effects on Memory, Motor Performance and Anxiety

The Cannabis plant contains more than 100 currently known phytocannabinoids. Regarding the rising consumption of the non-psychotropic phytocannabinoid cannabidiol (CBD) in people’s everyday life (e.g., beauty products, food and beverages), the importance of studies on the influence of CBD on healthy humans and rodents is evident. Therefore, the behavioral profile of CBD was investigated with […]

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Dietary Fat is Not a Major Determinant of Body Fat

The percentage of energy from fat in diets has been thought to be an important determinant of body fat, and several mechanisms have been proposed. Comparisons of diets and the prevalence of obesity between affluent and poor countries have been used to support this relationship, but these contrasts are seriously confounded by differences in physical […]

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What is Metabolic Syndrome Anyway?

Dr. Lustig specializes in the field of neuroendocrinology, with an emphasis on the regulation of energy balance by the central nervous system. His research and clinical practice has focused on childhood obesity and diabetes. Dr. Lustig holds a Bachelor’s in Science from MIT, a Doctorate in Medicine from Cornell University Medical College, and a Master’s […]

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Cancer Statistics, Trends, and Multiple Primary Cancer Analyses

An overview of cancer statistics and trends for selected cancers and all sites combined are given based on data from the Surveillance, Epidemiology, and End Results Program. Median age at diagnosis for all sites combined shows a 2-year increase from 1974 through 1978 to 1999 through 2003. Changes in cancer incidence rates from 1975 through […]

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Nutrition and Cancer – Time to Rethink

In 1931 Otto Warburg received the Nobel Prize for showing that cancer cells have an absolute requirement to use glucose for their energy requirements since they lack proper mitochondrial function for oxidizing fats. This suggests that nutritional factors in particular low or high carbohydrate diets might influence cancer outcomes differently. In my presentation I will […]

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The Impact of Dietary Changes in the Context of Modern Medicine

Medical talk will be around diet in the context of treatments of heart disease. Main topics to be covered: 1. Coronary stents, 2. Statins (primary and secondary prevention) 3. Communication of risk/informed consent 4. WHO figures on CVD 5. Smoking and heart disease 6. Saturated fat and heart disease 7. Tom Frieden’s CDC-health impact pyramid […]

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Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain

We investigated whether ultra-processed foods affect energy intake in 20 weight-stable adults, aged (mean ± SE) 31.2 ± 1.6 years and BMI = 27 ± 1.5 kg/m2. Subjects were admitted to the NIH Clinical Center and randomized to receive either ultra-processed or unprocessed diets for 2 weeks immediately followed by the alternate diet for 2 weeks. Meals were designed to be matched […]

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