Cannabidiol increases the nociceptive threshold in a preclinical model of Parkinson’s disease

Highlights• The CBD treatment decreases hyperalgesia and allodynia in experimental parkinsonism. • The inverse agonist of the CB1 receptor prevents the antinociceptive effect of CBD. • FAAH inhibitor or TRPV1 antagonist potentiates the CBD antinociceptive effect. Abstract Medications that improve pain threshold can be useful in the pharmacotherapy of Parkinson’s disease (PD). Pain is a […]

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More than 100 million Americans have diabetes or prediabetes

Diabetes growth rate steady, adding to health care burden   More than 100 million U.S. adults are now living with diabetes or prediabetes, according to a new reportCdc-pdf released today by the Centers for Disease Control and Prevention (CDC). The report finds that as of 2015, 30.3 million Americans – 9.4 percent of the U.S. population –have […]

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Pediatric Metabolic and Bariatric Surgery: Evidence, Barriers, and Best Practices

Severe obesity among youth is an “epidemic within an epidemic” and portends a shortened life expectancy for today’s children compared with those of their parents’ generation. Severe obesity has outpaced less severe forms of childhood obesity in prevalence, and it disproportionately affects adolescents. Emerging evidence has linked severe obesity to the development and progression of […]

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Scientists reveal the relationship between sugar and cancer

A nine-year joint research project conducted by VIB, KU Leuven and VUB has led to a crucial breakthrough in cancer research. Scientists have clarified how the Warburg effect, a phenomenon in which cancer cells rapidly break down sugars, stimulates tumor growth. This discovery provides evidence for a positive correlation between sugar and cancer, which may […]

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Sugar – the elephant in the kitchen

Robert H. Lustig is an American pediatric endocrinologist at the University of California, San Francisco (UCSF) where he is a Professor of Clinical Pediatrics. Dr. Lustig assesses the health dangers of sugar and its link to Type-2 diabetes and the global obesity epidemic. He is the author of several books and many articles on childhood […]

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On the keto diet? Ditch the cheat day

“The ketogenic — or keto — diet has become very common for weight loss or to manage diseases like type 2 diabetes,” says Jonathan Little, associate professor in the School of Health and Exercise Sciences at UBCO and study senior author. “It consists of eating foods rich in fats, moderate in protein, but very low […]

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The True Causes of Heart Disease are Not What You Think!

Finally got hold of the man who more than anyone, has deep-dived into the root causes of heart disease – without bias – just fixated with finding the truth. I’m of course referring to Dr. Malcolm Kendrick, who has created the 65-part (and growing) series “What Causes Heart Disease?“.See index below for a gist of what […]

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Hypoascorbemia induces atherosclerosis and vascular deposition of lipoprotein(a)

Lipoprotein(a), a variant of LDL carrying the adhesive glycoprotein apo(a), is a leading risk factor for cardiovascular disease. Lipoprotein(a) (Lp(a)) is found in humans and subhuman primates but rarely in lower mammals. Better understanding of the evolutionary advantage of this molecule should elucidate its physiological role. We developed a new mouse model with two characteristics […]

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Life long choline supplementation may improve cognitive function in Alzheimer’s patients, finds study

Life long choline supplementation may improve cognitive function in Alzheimer’s patients, revealed a study published in the journal, Aging Cell.  Researchers from ASU-Banner Neurodegenerative Disease Research Center (NDRC) checked whether choline supplementation could alleviate the alleviate effect of Alzheimer’s disease. Choline acts to protect the brain from Alzheimer’s disease in at least two ways, both […]

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Sugar is Not a Treat

Sugar is hiding everywhere in today’s widely-accepted diet, but meanwhile its devastating effects are creating more deaths than automobile accidents. In this eye-opening talk, Dr. Jody Stanislaw, a Naturopathic Doctor who has been studying the negative effects of sugar since being diagnosed with type 1 diabetes at the age of 7, dives into how the […]

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