Dietary Restriction and Fasting Increase Lifespan

AMPK and DR maintain mitochondrial network homeostasis with age Mitochondrial fusion and fission are required for DR- and AMPK-mediated longevity Preserving mitochondrial homeostasis increases lifespan via fatty acid oxidation These longevity pathways require coordination between mitochondria and peroxisomes   Mitochondrial network remodeling between fused and fragmented states facilitates mitophagy, interaction with other organelles, and metabolic […]

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‘Carbohydrates are killing us’

This year, more than 610,000 Americans will die from heart disease. It’s the leading cause of death for both men and women. For decades, doctors and nutritionists prescribed low-fat diets to people trying to lower their risk of heart disease. Saturated fats in meats and dairy products were thought to clog our arteries. Grains — […]

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Genetic Study Supports Carbohydrate-Insulin Model of Obesity

According to the Carbohydrate-Insulin Model of Obesity (CIM), the processed carbohydrates that flooded our diet during the low-fat diet craze undermine our metabolism and drive weight gain. Put simply: Processed carbohydrates — think white bread, white rice, potato products, low -fat snacks — raise insulin more than any other food, calorie for calorie. This is just Nutrition, 101. Insulin is the Miracle-Gro […]

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Carbon dioxide in carbonated beverages induces ghrelin release and increased food consumption in male rats: Implications on the onset of obesity

The dangerous health risks associated with obesity makes it a very serious public health issue. Numerous studies verified a correlation between the increase in obesity and the parallel increase in soft drink consumption among world populations. The effects of one main component in soft drinks namely the carbon dioxide gas has not been studied thoroughly in any […]

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Ketogenic diet may boost targeted cancer therapy

A very low carbohydrate, high-fat diet called the ketogenic diet may improve the effectiveness of an emerging class of cancer drugs, according to a study in mice by investigators at Weill Cornell Medicine, Columbia University Irving Medical Center and NewYork-Presbyterian. In a study published in Nature on July 4, scientists provide a possible explanation for why the […]

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Distinct Circadian Signatures in Liver and Gut Clocks Revealed by Ketogenic Diet

KD induces tissue-specific reprogramming of the circadian clock in liver and gut KD induces an increase in liver BMAL1 chromatin recruitment and amplitude of CCGs KD drives tissue-specific oscillation of PPARα and its target genes Oscillation of βOHB in gut and serum parallels gut-specific cycling of H3 acetylation   The circadian clock orchestrates rhythms in […]

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Continuous Remote Care Model Utilizing Nutritional Ketosis Improves Type 2 Diabetes Risk Factors in Patients with Prediabetes

Prediabetes (preT2D) is a major U.S. public health concern, as over 84 million adults are at greater risk of cardiovascular disease and progression to type 2 diabetes (T2D). Abnormal glucose, BMI, blood pressure, and blood lipids are risk factors for progression to T2D. The purpose of this single-arm prospective longitudinal investigation was to assess change […]

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Dr. Maryanne Demasi – ‘Statin Wars: Have we been misled by the evidence?’

Dr. Maryanne Demasi is a former medical scientist who completed her PhD in Medicine at the University of Adelaide. Her research focused on the pathology of Rheumatoid arthritis and potential therapies. Her innovative research has appeared in several internationally published medical journals. Leaving her lab coat behind, Maryanne accepted a position as a political advisor […]

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Reverse and Prevent Diabetes with Dr. Brian Mowll

Type 2 Diabetes and pre-diabetes is a real threat for emotional eaters. But it can be reversed. Dr. Brian Mowll is the founder and medical director of SweetLife® Diabetes Health Centers. He coaches clients worldwide by showing them how optimize their health and metabolism, control blood sugar, and reverse type 2 diabetes using a natural, […]

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