Dairy Fats and Cardiovascular Disease: Do We Really Need to Be Concerned?

Cardiovascular diseases (CVD) remain a major cause of death and morbidity globally and diet plays a crucial role in the disease prevention and pathology. The negative perception of dairy fats stems from the effort to reduce dietary saturated fatty acid (SFA) intake due to their association with increased cholesterol levels upon consumption and the increased […]

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High Dairy Fat Intake Related to Less Central Obesity

The objective of the study was to understand the associations between dairy fat intake and development of central obesity. The study was designed on a prospective population-based cohort study with two surveys 12 years apart. Nine municipalities selected from different parts of Sweden representing the rural areas in the country. 1782 men (farmers and non-farmers) aged […]

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Consumption of Extra Virgin Olive Oil Improves Body Composition and Blood Pressure

Despite the fact that extra virgin olive oil (EVOO) is widely used in obese individuals to treat cardiovascular diseases, the role of EVOO on weight/fat reduction remains unclear. We investigated the effects of energy-restricted diet containing EVOO on body composition and metabolic disruptions related to obesity. This is a randomized, double-blinded, placebo-controlled clinical trial in […]

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Consumption of Honey, Sucrose, and High-Fructose Corn Syrup Produces Similar Metabolic Effects in Glucose-Tolerant and Intolerant Individuals

Public health recommendations call for a reduction in added sugars; however, controversy exists over whether all nutritive sweeteners produce similar metabolic effects. Objective: The objective was to compare the effects of the chronic consumption of 3 nutritive sweeteners [honey, sucrose, and high-fructose corn syrup containing 55% fructose (HFCS55)] on circulating glucose, insulin, lipids, and inflammatory markers; […]

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Woman Followed a Keto Diet and Lost 100 Pounds

Elena Juarez punched and food-prepped her way to losing 100 pounds. But her weight-loss journeykicked off with a serious health scare. On her own, Juarez started following a paleo-friendly diet challenge that included kickboxing That’s when she heard about the ketogenic diet. Six weeks later, she adopted the trendy high-fat, low-carb plan. One hundred lost pounds later, she credits going keto and sticking with kickboxing for […]

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Fructose and Cardiometabolic Health

Recent attention has focused on fructose as having a unique role in the pathogenesis of cardiometabolic diseases. However, because we rarely consume fructose in isolation, the major source of fructose in the diet comes from fructose-containing sugars, sucrose and high fructose corn syrup, in sugar-sweetened beverages and foods. Intake of sugar-sweetened beverages has been consistently […]

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Dietary Restriction Increases Lifespan

Mitochondrial network remodeling between fused and fragmented states facilitates mitophagy, interaction with other organelles, and metabolic flexibility. Aging is associated with a loss of mitochondrial network homeostasis, but cellular processes causally linking these changes to organismal senescence remain unclear. Here, we show that AMP-activated protein kinase (AMPK) and dietary restriction (DR) promote longevity in C. elegans via maintaining […]

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Distinct Circadian Signatures in Liver and Gut Clocks Revealed by Ketogenic Diet

• KD induces tissue-specific reprogramming of the circadian clock in liver and gut • KD induces an increase in liver BMAL1 chromatin recruitment and amplitude of CCGs • KD drives tissue-specific oscillation of PPARα and its target genes • Oscillation of βOHB in gut and serum parallels gut-specific cycling of H3 acetylation The circadian clock […]

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Mitochondria: The Ketogenic Diet—A Metabolism-Based Therapy

Mitochondria are the energy-producing organelles of the cell, generating ATP via oxidative phosphorylation mainly by using pyruvate derived from glycolytic processing of glucose. Ketone bodies generated by fatty acid oxidation can serve as alternative metabolites for aerobic energy production. The ketogenic diet, which is high in fat and low in carbohydrates, mimics the metabolic state […]

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What Will Happen to Your Body If You Walk Every Day

Walking is a totally free, easy exercise that requires little effort, and benefits not only your physical but also your mental well-being. If you’re looking for a simple yet very effective way of losing weight and improving your overall health, walking is something just for you. People who are physically active throughout their life are […]

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