White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer’s Disease

White matter degeneration is a pathological hallmark of neurodegenerative diseases including Alzheimer’s. Age remains the greatest risk factor for Alzheimer’s and the prevalence of age-related late onset Alzheimer’s is greatest in females. We investigated mechanisms underlying white matter degeneration in an animal model consistent with the sex at greatest Alzheimer’s risk. Results of these analyses […]

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Saturated fats no longer the true enemy

Saturated fats are not the enemy. But processed foods are, according to a new policy statement from the Heart and Stroke Foundation of Canada. On Thursday, the foundation released a new policy statement that questions conventional wisdom about the dangers of saturated fats on the heart. Saturated fat is found naturally in red meat, dairy […]

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Microbial regulation of microRNA expression in the amygdala and prefrontal cortex

There is growing evidence for a role of the gut microbiome in shaping behaviour relevant to many psychiatric and neurological disorders. Preclinical studies using germ-free (GF) animals have been essential in contributing to our current understanding of the potential importance of the host microbiome for neurodevelopment and behaviour. In particular, it has been repeatedly demonstrated […]

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Juice Is Terrible for Children

Quick: think back to childhood (if you’ve reached the scary clown you’ve gone too far). What did your parents or guardians give you to keep you quiet? If you’re anything like most parents, it was juice. But here’s the thing: juice is bad for you. According to pediatric professors Erika R. Cheng, Lauren G. Fiechtner and Aaron E. Carroll, […]

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No Significant Association with Dairy Fat Intake and Heart Disease

Controversy has emerged about the benefits compared with harms of dairy fat, including concerns over long-term effects. Previous observational studies have assessed self-reported estimates of consumption or a single biomarker measure at baseline, which may lead to suboptimal estimation of true risk. The aim of this study was to investigate prospective associations of serial measures […]

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Dr. Berg Interviews Dr. Jason Fung on Intermittent Fasting & Losing Weight

Dr. Eric Berg interviews Dr. Jason Fung on intermittent fasting, obesity, diabetes and insulin. Dr. Fung discusses calories and how its not about the calories, it’s about the hormones, specifically insulin. Insulin makes you fat. Diets that lower calories fail repeatedly. The cause of obesity is too much insulin. Lowering your carbs and intermittent fasting. […]

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Vitamin K Dependent Proteins and the Role of Vitamin K2 in the Modulation of Vascular Calcification: A Review

Vascular calcification, a cause of cardiovascular morbidity and mortality, is an actively regulated process involving vitamin K dependent proteins (VKDPs) among others. Vitamin K is an essential micronutrient, present in plants and animal fermented products that plays an important role as a cofactor for the post-translational γ-carboxylation of glutamic acid residues in a number of […]

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Dietary Intake of Menaquinone Is Associated with a Reduced Risk of Coronary Heart Disease: The Rotterdam Study

Vitamin K–dependent proteins, including matrix Gla-protein, have been shown to inhibit vascular calcification. Activation of these proteins via carboxylation depends on the availability of vitamin K. We examined whether dietary intake of phylloquinone (vitamin K-1) and menaquinone (vitamin K-2) were related to aortic calcification and coronary heart disease (CHD) in the population-based Rotterdam Study. The […]

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Juice Is Not Healthy

Obesity affects 40 percent of adults and 19 percent of children in the United States and accounts for more than $168 billion in health care spendingeach year. Sugary beverages are thought to be one of the major drivers of the obesity epidemic. These drinks (think soda and sports drinks) are the largest single source of added sugars for Americans and contribute, on […]

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