The case for low carbohydrate diets in diabetes management

A low fat, high carbohydrate diet in combination with regular exercise is the traditional recommendation for treating diabetes. Compliance with these lifestyle modifications is less than satisfactory, however, and a high carbohydrate diet raises postprandial plasma glucose and insulin secretion, thereby increasing risk of CVD, hypertension, dyslipidemia, obesity and diabetes. Moreover, the current epidemic of […]

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Sugar, Processed Food, and Obesity – Sugar Is In Everything – Robert Lustig MD

Sugar, Processed Food, & Obesity: Sugar Is In Everything – Robert Lustig, M.D. It’s increasingly hard to eat less sugar, as market shelves are filled with sugary products. In the past ten years alone, global sugar intake has risen by ten percent. In what’s not the first and surely not the last appeal of the […]

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Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet

We recently proposed that the biological markers improved by carbohydrate restriction were precisely those that define the metabolic syndrome (MetS), and that the common thread was regulation of insulin as a control element. We specifically tested the idea with a 12‐week study comparing two hypocaloric diets (~1,500 kcal): a carbohydrate‐restricted diet (CRD) (%carbohydrate:fat:protein = 12:59:28) […]

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KetoNutrition: From Science to Application

An impressive body of scientific evidence over the last 15 years documents long term benefits of carbohydrate-restricted, especially ketogenic, diets. We now understand molecular mechanisms and why they work. Popular books and articles now challenge the advice ‘carbohydrates are good and fats are bad.’ Circa mid-19th century urinary ketones were identified in diabetics sealing their […]

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High Blood Sugar Can Cause Heart Disease

Type 2 diabetes can increase the risk of developing heart disease if the blood sugar condition is not controlled properly. If you have diabetes, how can you lower your risk of complications such as heart attacks and strokes? Type 2 diabetes is when the level of sugar in the blood is too high. The condition is lifelong, […]

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Should dietary fat guidelines have been introduced?

Zoë Harcombe was the first pupil from her school to graduate from Cambridge University. While studying maths and economics at this historic institution, Zoë set out to answer the million dollar question – “Why do you overeat? When all you want is to be slim?” This became the title of Zoë’s first book – published […]

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Effects of Sugar on Blood Pressure and Lipids

Sugar has been suggested as a central risk factor in the development of noncommunicable diseases. We assessed the evidence of the effects of free sugars compared with complex carbohydrates on selected cardiovascular disease risk factors. DWe conducted a systematic review and meta-analysis of intervention trials to compare diets that provide a given amount of energy […]

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Two Type 2 Diabetes Drugs Linked to Higher Risk of Heart Disease

Are second-line antidiabetic medications (ADMs) associated with cardiovascular events among insured adult patients with type 2 diabetes who are initiating second-line therapy? This cohort study of 132 737 adults with type 2 diabetes found that glucagon-like peptide 1 receptor agonists, dipeptidyl peptidase 4 inhibitors, and sodium-glucose cotransporter 2 inhibitors were associated with similar cardiovascular outcomes. Sulfonylureas […]

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Deaths Attributable to Diabetes in the United States: Comparison of Data Sources and Estimation Approaches

We estimated population attributable fractions (PAF) for cohorts aged 30–84 who were surveyed in the National Health Interview Survey (NHIS) between 1997 and 2009 (N = 282,322) and in the National Health and Nutrition Examination Survey (NHANES) between 1999 and 2010 (N = 21,814). Cohort members were followed prospectively for mortality through 2011. We identified […]

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