Professor Valter Longo: fasting and healthy aging

Inspired by a mentor’s extreme experiments with caloric restriction, USC Leonard Davis School of Gerontology Professor Valter Longo explores how fasting-mimicking diets might help prevent disease, promote healthy aging, and prolong our ability to stay young. Quotes from this episode Longo’s ambitious goal for human longevity: “I want to optimize the chance for people to […]

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What is Metabolic Syndrome Anyway?

JumpstartMD is a medical practice dedicated to pre-emptive medicine through lifestyle changes and healthy, sustainable weight loss. Personalized program based on proven nutritional science, one-on-one lifestyle counseling and real, fresh food. Founded by Stanford trained physicians and board-certified Diplomates of the American Board of Obesity Medicine. PPO, HSA and FSA reimbursement support provided to patients. […]

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Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet

We recently proposed that the biological markers improved by carbohydrate restriction were precisely those that define the metabolic syndrome (MetS), and that the common thread was regulation of insulin as a control element. We specifically tested the idea with a 12‐week study comparing two hypocaloric diets (~1,500 kcal): a carbohydrate‐restricted diet (CRD) (%carbohydrate:fat:protein = 12:59:28) […]

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To Fight Fatty Liver, Avoid Sugary Foods and Drinks

Pediatric guidelines for the management of nonalcoholic fatty liver disease (NAFLD) recommend a healthy diet as treatment. Reduction of sugary foods and beverages is a plausible treatment. In this randomized clinical trial that included 40 adolescent boys aged 11 to 16 years with nonalcoholic fatty liver disease followed up for 8 weeks, provision of a […]

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The Ketogenic Diet—A Metabolism-Based Therapy

Mitochondria are the energy-producing organelles of the cell, generating ATP via oxidative phosphorylation mainly by using pyruvate derived from glycolytic processing of glucose. Ketone bodies generated by fatty acid oxidation can serve as alternative metabolites for aerobic energy production. The ketogenic diet, which is high in fat and low in carbohydrates, mimics the metabolic state […]

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Timing of food intake is more potent than habitual voluntary exercise to prevent diet-induced obesity in mice

Inappropriate eating habits such as eating late at night are associated with risk for abnormal weight-gain and adiposity. We previously reported that time-imposed feeding during the daytime (inactive phase) induces obesity and metabolic disorders accompanied by physical inactivity in mice. The present study compares metabolic changes induced in mice by time-imposed feeding under voluntary wheel-running […]

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Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance

Study is based on 64 adults aged 18-65 years adults, with a body mass index of 25 or more. IAfter 12% (within 2%) weight loss on a run-in diet, participants were randomly assigned to one of three test diets according to carbohydrate content (high, 60%, n=54; moderate, 40%, n=53; or low, 20%, n=57) for 20 […]

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‘Therapeutic Fasting – Solving the Two-Compartment Problem’

Intermittent fasting is the ancient secret of health. It is ancient because it has been practiced throughout all of human history. It’s a secret because this powerful habit has been virtually forgotten. But now many people are re-discovering this dietary intervention. It can carry huge benefits if it is done right: weight loss, increased energy, […]

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Are T2D Patients Monitoring Blood Glucose Needlessly?

Claims data suggest 1 in 7 patients do unnecessary daily fingersticks. Many people with type 2 diabetes may be overusing self-monitoring blood glucose supplies, according to a new study. In a retrospective analysis of insurance claims for more than 370,000 individuals with type 2 diabetes not on insulin, 14% were probably testing themselves too often, […]

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