Targeting Metabolism with A Ketogenic Diet During the Treatment of Glioblastoma Multiforme

Retrospective data suggests that low serum glucose levels during the treatment of glioblastoma multiforme (GBM) may improve clinical outcomes. As such, many patients are implementing a ketogenic diet (KD) in order to decrease serum glucose flux while simultaneously elevating circulating ketones during radiation therapy and chemotherapy for the treatment of GBM. With IRB approval, a […]

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Calories, Carbohydrates, and Cancer Therapy

Aggressive tumors typically demonstrate a high glycolytic rate, which results in resistance to radiation therapy and cancer progression via several molecular and physiologic mechanisms. Intriguingly, many of these mechanisms utilize the same molecular pathways that are altered through calorie and/or carbohydrate restriction. Furthermore, poorer prognosis in cancer patients who display a glycolytic phenotype characterized by […]

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Intermittent Fasting: Transformational Technique

Two-thirds of women 40-59 years old are overweight and more than 1/2 are obese. Intermittent fasting can help women lose weight effectively. And can have profound impact on bio-physical profiles, but also improved self esteem and interpersonal relationships. It is easy to implement, it is inexpensive and flexible. Cynthia is a Western medicine trained nurse […]

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The Impact of Dietary Changes in the Context of Modern Medicine

Medical talk will be around diet in the context of treatments of heart disease. Main topics to be covered: 1. Coronary stents, 2. Statins (primary and secondary prevention) 3. Communication of risk/informed consent 4. WHO figures on CVD 5. Smoking and heart disease 6. Saturated fat and heart disease 7. Tom Frieden’s CDC-health impact pyramid […]

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Researchers Discover How Eating Feeds into the Body Clock

New research has found it is not just what you eat, but when you eat that is important, knowledge which could improve the health of shift workers and people suffering from jet lag. The MRC-funded study, published today in the journal Cell, is the first to identify insulin as a primary signal that helps communicate the […]

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Professor Valter Longo: fasting and healthy aging

Inspired by a mentor’s extreme experiments with caloric restriction, USC Leonard Davis School of Gerontology Professor Valter Longo explores how fasting-mimicking diets might help prevent disease, promote healthy aging, and prolong our ability to stay young. Quotes from this episode Longo’s ambitious goal for human longevity: “I want to optimize the chance for people to […]

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What is Metabolic Syndrome Anyway?

JumpstartMD is a medical practice dedicated to pre-emptive medicine through lifestyle changes and healthy, sustainable weight loss. Personalized program based on proven nutritional science, one-on-one lifestyle counseling and real, fresh food. Founded by Stanford trained physicians and board-certified Diplomates of the American Board of Obesity Medicine. PPO, HSA and FSA reimbursement support provided to patients. […]

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Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet

We recently proposed that the biological markers improved by carbohydrate restriction were precisely those that define the metabolic syndrome (MetS), and that the common thread was regulation of insulin as a control element. We specifically tested the idea with a 12‐week study comparing two hypocaloric diets (~1,500 kcal): a carbohydrate‐restricted diet (CRD) (%carbohydrate:fat:protein = 12:59:28) […]

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To Fight Fatty Liver, Avoid Sugary Foods and Drinks

Pediatric guidelines for the management of nonalcoholic fatty liver disease (NAFLD) recommend a healthy diet as treatment. Reduction of sugary foods and beverages is a plausible treatment. In this randomized clinical trial that included 40 adolescent boys aged 11 to 16 years with nonalcoholic fatty liver disease followed up for 8 weeks, provision of a […]

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