Postmarket Safety Events Among Novel Therapeutics Approved by the US Food and Drug Administration Between 2001 and 2010

Postmarket safety events of novel pharmaceuticals and biologics occur when new safety risks are identified after initial regulatory approval of these therapeutics. These safety events can change how novel therapeutics are used in clinical practice and inform patient and clinician decision making. The Jama Network: Postmarket Safety Events Among Novel Therapeutics Approved by the US […]

Read More »

Ketogenic Diet Sensitizes Glucose Control of Hippocampal Excitability

A high-fat, low-carbohydrate ketogenic diet is an effective treatment for refractory epilepsy, yet myriad metabolic effects in vivo have not been reconciled clearly with neuronal effects. A ketogenic diet limits blood glucose, and produces ketone bodies from β-oxidation of lipids. Studies have explored changes in ketone bodies and/or glucose in the effects of the ketogenic […]

Read More »