Diabetes, Adult Neurogenesis and Brain Remodeling

The prevalence of diabetes rapidly increased during the last decades in association with important changes in lifestyle. Diabetes and hyperglycemia are well-known for inducing deleterious effects on physiologic processes, increasing for instance cardiovascular diseases, nephropathy, retinopathy and foot ulceration. Interestingly, diabetes also impairs brain morphology and functions such as  decreased neurogenesis (proliferation, differentiation and cell […]

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Brain fuel metabolism, aging, and Alzheimer’s disease

Lower brain glucose metabolism is present before the onset of clinically measurable cognitive decline in two groups of people at risk of Alzheimer’s disease–carriers of apolipoprotein E4, and in those with a maternal family history of AD. Supported by emerging evidence from in vitro and animal studies, these reports suggest that brain hypometabolism may precede […]

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The Role of Magnesium in Depression Treatment

Current treatment options for depression are limited by efficacy, cost, availability, side effects, and acceptability to patients. Several studies have looked at the association between magnesium and depression, yet its role in symptom management is unclear. The objective of this trial was to test whether supplementation with over-the-counter magnesium chloride improves symptoms of depression. An […]

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Ketogenic Diet For Cancer, Epilepsy & Diabetes With Dr. Dominic D’Agostino

Is the ketogenic diet for cancer healthy? Does it prevent epilepsy, seizures and diabetes? Dr. Dominic D’Agostino talks about the keto diet for not just preventing cancer but also treating it. The ketogenic diet helps to stop cancer cells from using sugar to grow and even causes apoptosis (cell death) in certain instances. Dr. Dom […]

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The Ketogenic Diet: Adolescents Can Do It, Too

The purpose of the study is to determine both the efficacy of and compliance with the ketogenic diet in the adolescent population. A retrospective study of 45 patients, aged 12–19 years, consecutively enrolled in a ketogenic diet program from 1994 to 2002, was performed. Thirty‐seven patients were from The Johns Hopkins Medical Institutions; eight were […]

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Ketogenic Diet Exhibits Anti‐Inflammatory Properties

The ketogenic diet (KD) is an established treatment for refractory epilepsy, including some inflammation‐induced epileptic encephalopathies. In a lipopolysaccharide (LPS)–induced fever model in rats, we found that animals given the KD for 14 days showed less fever and lower proinflammatory cytokine levels than control animals. However, KD rats exhibited a decrease in circulating levels of […]

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Children eat three times as much sugar as they should

The average child has eaten their entire childhood sugar allowance by the age of ten, according to health chiefs. Figures published today by Public Health England (PHE) estimate that young children are eating almost three times as much sugar as they should, the equivalent of about eight cubes too many a day. Parents have been […]

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The Ketogenic Diet—A Metabolism-Based Therapy

Mitochondria are the energy-producing organelles of the cell, generating ATP via oxidative phosphorylation mainly by using pyruvate derived from glycolytic processing of glucose. Ketone bodies generated by fatty acid oxidation can serve as alternative metabolites for aerobic energy production. The ketogenic diet, which is high in fat and low in carbohydrates, mimics the metabolic state […]

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Keto Diet May Increase Memory, Reduce Mortality

Two new studies, both conducted in mice, support each other’s findings: that the ketogenic, or “keto,” diet may improve memory in old age as well as prolong lifespan. The ketogenic diet, which is more commonly known as the keto diet, aims to reduce carbohydrate intake in favor of consuming more fat and sufficient protein. Recently, this diet type […]

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Benefits of Ketogenic Diet for Management of Type Two Diabetes: A Review

The prevalence of type two diabetes (T2D) has been increasing sharply worldwide. Many recent studies have been done to determine the effective strategies for better management of type two diabetes. One of these strategies was the Ketogenic Diet, which when performed on rats and human showed very impressive results. The benefits of having some ketone […]

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