Sugar addiction: Is it real?

In animal studies, sugar has been found to produce more symptoms than is required to be considered an addictive substance. Animal data has shown significant overlap between the consumption of added sugars and drug-like effects, including bingeing, craving, tolerance, withdrawal, cross-sensitisation, cross-tolerance, cross-dependence, reward and opioid effects. Sugar addiction seems to be dependence to the […]

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Role of The Gut Microbiota in Nutrition and Health

Microbiome refers to the collective genomes of the micro-organisms in a particular environment, and microbiota is the community of micro-organisms themselves. Approximately 100 trillion micro-organisms (most of them bacteria, but also viruses, fungi, and protozoa) exist in the human gastrointestinal tract—the microbiome is now best thought of as a virtual organ of the body. The […]

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Examining the Health Effects of Fructose

In the 1990s, excessive fat consumption was commonly believed to be the main cause of obesity. High sugar consumption was often considered to be innocuous and possibly protective against obesity by displacing dietary fat. A decade later, the American Heart Association linked intake of added sugars to weight gain and recommended substantial decreases in consumption […]

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Are T2D Patients Monitoring Blood Glucose Needlessly?

Claims data suggest 1 in 7 patients do unnecessary daily fingersticks. Many people with type 2 diabetes may be overusing self-monitoring blood glucose supplies, according to a new study. In a retrospective analysis of insurance claims for more than 370,000 individuals with type 2 diabetes not on insulin, 14% were probably testing themselves too often, […]

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Evidence Behind the Advice About Salt

Low-sodium diets are widely recommended for people who have a variety of ailments, but there’s little proof they help those with heart failure. Despite a number of studies questioning the usefulness of very low-salt diets in the last few years, most major medical organizations continue to recommend them. We would assume that they do so from a strong base of evidence. […]

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Obesity: Replacing Bias With Curiosity

Visualize a woman with obesity. Do you assume she eats all day and never gets off the couch? Picture a man with obesity. Do you think of him as lazy and unsuccessful? Are you secretly (or not so secretly) critical of those you love who have obesity? Do you yourself live with obesity, self-judgment, and shame? When we […]

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Eating Particular Diets Can Help Heal Us

Between 2016 and 2018, postdoctoral researchers in Cantley’s laboratory and mine established that this strategy worked on several mouse cancers, and on human cancers implanted into mice. By 2019, working with clinicians at Columbia, Cornell and Memorial Sloan Kettering, we hope to begin a study in humans with lymphomas, endometrial cancer and breast cancer, to […]

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Sweetening of The Global Diet

Evidence suggests that excessive intake of added sugars has adverse effects on cardiometabolic health, which is consistent with many reviews and consensus reports from WHO and other unbiased sources. 74% of products in the US food supply contain caloric or low-calorie sweeteners, or both. Of all packaged foods and beverages purchased by a nationally representative […]

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Resurgence of Diabetes-Related Nontraumatic Lower Extremity Amputation in U.S Population

The study had as objective to determine whether declining trends in lower extremity amputations have continued into the current decade. We calculated hospitalization rates for nontraumatic lower extremity amputation (NLEA) for the years 2000–2015 using nationally representative, serial cross-sectional data from the Nationwide Inpatient Sample on NLEA procedures and from the National Health Interview Survey […]

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NCD Countdown 2030: Worldwide Trends in Non-Communicable Disease Mortality

The third UN High-Level Meeting on Non-Communicable Diseases (NCDs) on Sept 27, 2018, will review national and global progress towards the prevention and control of NCDs, and provide an opportunity to renew, reinforce, and enhance commitments to reduce their burden. NCD Countdown 2030 is an independent collaboration to inform policies that aim to reduce the […]

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