Prolonged Fasting Increases Cell Regeneration and Reverse Immunosuppression

Immune system defects are at the center of aging and a range of diseases. Here, we show that prolonged fasting reduces circulating IGF-1 levels and PKA activity in various cell populations, leading to signal transduction changes in long-term hematopoietic stem cells (LT-HSCs) and niche cells that promote stress resistance, self-renewal, and lineage-balanced regeneration. Multiple cycles […]

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Fasting Regenerates Your Entire Immune System

Prolonged fasting downregulates a IGF-1/PKA pathway in stem Prolong fasting protects hematopoietic cells from chemotoxicity Prolonged fasting cycles promote HSC self-renewal to reverse immunosuppression Inhibition of IGF-1 or PKA signaling mimics the effects of prolonged Immune system defects are at the center of aging and a range of diseases. Here, we show that prolonged fasting […]

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Does Fat Really Burn in the Flame of Carbohydrate?

Dr. Michael R. Eades received his BSCE degree in Civil Engineering from California Polytechnic University (Cal Poly), Pamona, California and his MD from the University of Arkansas Medical Sciences (UAMS). After completing training in General Surgery as UAMS, Dr. Eades (along with his wife) founded Medi-Stat Medical Clinics, a chain of general family medicine outpatient […]

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Sugar is Almost a Metabolic Poison for Type 2 Diabetes Patients

David Unwin, Fellow of the Royal College of General Practitioners (FRCGP), and Senior Partner of the Norwood Surgery presented “Real life experiences: Weighing up the pros and cons of drugs and lifestyle choices properly before making choices” at the Swiss Re Institute’s Expert Forum on diabetes, Rüschlikon, 9 – 10 October 2017.

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Substantial and Sustained Improvements in Blood Pressure, Weight and Lipid Profiles from a Carbohydrate Restricted Diet: An Observational Study of Insulin Resistant Patients in Primary Care

Hypertension is the second biggest known global risk factor for disease after poor diet; perhaps lifestyle interventions are underutilized? In a previous small pilot study, it was found that a low carbohydrate diet was associated with significant improvements in blood pressure, weight, ‘deprescribing’ of medications and lipid profiles. We were interested to investigate if these […]

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‘Does Fiber Make You Fat? – The Gut’s Effect on Weight and Metabolism’

Erynn Kay graduated from Northern Arizona University in 2005 with a Bachelors of Science in Microbiology. She then went on to earn a Masters of Medical Science in Physician Assistant Studies at Midwestern University in Glendale, Arizona in 2009. Erynn is a board certified, licensed Physician Assistant who works along side Dr. Jeffry Gerber (Denver’s […]

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Bread and Other Edible Agents of Mental Disease

Perhaps because gastroenterology, immunology, toxicology, and the nutrition and agricultural sciences are outside of their competence and responsibility, psychologists and psychiatrists typically fail to appreciate the impact that food can have on their patients’ condition. Here we attempt to help correct this situation by reviewing, in non-technical, plain English, how cereal grains—the world’s most abundant […]

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Chronic Inflammation Removes Motivation by Reducing Dopamine in the Brain

Why do we feel listless when we are recovering from an illness? The answer is, apparently, that low-grade chronic inflammation interferes with the dopaminergic signaling system in the brain that motivates us to do things. This was reported in a new paper published in the journal Trends in Cognitive Sciences. The research carried out at Emory […]

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