A Ketogenic Diet Improves Cognition

Age-related cognitive decline has been linked to a diverse set of neurobiological mechanisms, including bidirectional changes in proteins critical for neuron function. Importantly, these alterations are not uniform across the brain. For example, the hippocampus (HPC) and prefrontal cortex (PFC) show distinct patterns of dysfunction in advanced age. Because higher cognitive functions require large-scale interactions […]

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NCD Countdown 2030: Worldwide Trends in Non-Communicable Disease Mortality

The third UN High-Level Meeting on Non-Communicable Diseases (NCDs) on Sept 27, 2018, will review national and global progress towards the prevention and control of NCDs, and provide an opportunity to renew, reinforce, and enhance commitments to reduce their burden. NCD Countdown 2030 is an independent collaboration to inform policies that aim to reduce the […]

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Taking Steps to Better Health

Besides cardiovascular health, the established physical benefits of walking at a moderate pace (about three miles per hour) include: Lessened cancer risk Reduced mental decline, including dementia Lowered chance of heart disease Improved joint function Stronger bones Reduced risk for diabetes Energy boost The benefits of walking extend to mental perks as well. Walking increases the release of […]

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Sleep deprivation: Impact on cognitive performance

Today, prolonged wakefulness is a widespread phenomenon. Nevertheless, in the field of sleep and wakefulness, several unanswered questions remain. Prolonged wakefulness can be due to acute total sleep deprivation (SD) or to chronic partial sleep restriction. Although the latter is more common in everyday life, the effects of total SD have been examined more thoroughly. […]

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Healthy dietary indices and risk of depressive outcomes

With depression being the psychiatric disorder incurring the largest societal costs in developed countries, there is a need to gather evidence on the role of nutrition in depression, to help develop recommendations and guide future psychiatric healthcare. The aim of this systematic review was to synthesize the link between diet quality, measured using a range […]

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Ketogenic Diet as a Metabolic Therapy for Mood Disorders

Despite significant advances in pharmacological and non-pharmacological treatments, mood disorders remain a significant source of mental capital loss, with high rates of treatment resistance, requiring a coordinated effort in investigation and development of efficient, tolerable and accessible novel interventions. Ketogenic diet (KD) is a low-carb diet that substantially changes the energetic matrix of the body […]

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Not getting enough sleep seems to be even more deadly than we thought, new studies show

A trio of new studies show that too little or too much sleep is associated with an increased risk for cardiovascular disease.  Sleeping less than five hours per night raises the risk for a heart attack or stroke by about the same degree as smoking does, according one study in older men. This adds to a significant body of evidence that […]

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Microbial regulation of microRNA expression in the amygdala and prefrontal cortex

There is growing evidence for a role of the gut microbiome in shaping behaviour relevant to many psychiatric and neurological disorders. Preclinical studies using germ-free (GF) animals have been essential in contributing to our current understanding of the potential importance of the host microbiome for neurodevelopment and behaviour. In particular, it has been repeatedly demonstrated […]

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Antidepressant Use May Contribute to Long-Term Population Weight Gain

Researchers at King’s College London have found that patients prescribed any of the 12 most commonly used antidepressants were 21% more likely to experience an episode of gain weight than those not taking the drugs, (after adjusting for other factors which might affect this result). The full research is published in the BMJ. They also found […]

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What Will Happen to Your Body If You Walk Every Day

Walking is a totally free, easy exercise that requires little effort, and benefits not only your physical but also your mental well-being. If you’re looking for a simple yet very effective way of losing weight and improving your overall health, walking is something just for you. People who are physically active throughout their life are […]

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