Exercise for cognitive brain health in aging

We systematically appraised randomized controlled trials proposing exercise to influence cognition in older adults to (1) assess the methodologic quality using Cochrane criteria; (2) describe various exercise dose measures and assess their relationship with improved cognitive performance; and (3) identify consistent patterns of reported effects on cognition. There was overall good methodologic quality in all […]

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What Will Happen to Your Body If You Walk Every Day

Walking is a totally free, easy exercise that requires little effort, and benefits not only your physical but also your mental well-being. If you’re looking for a simple yet very effective way of losing weight and improving your overall health, walking is something just for you. People who are physically active throughout their life are […]

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What is Metabolic Syndrome, and Why are Children Getting It?

Metabolic syndrome is a clustering of at least three of the five following medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides and low high-density lipoprotein (HDL) levels. Metabolic syndrome is associated with the risk of developing cardiovascular disease and type 2 diabetes. In the US about a quarter of the adult population have metabolic syndrome, and the prevalence increases with age, with racial […]

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Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders

High-fat, low-carbohydrate diets, known as ketogenic diets, have been used as a non-pharmacological treatment for refractory epilepsy. A key mechanism of this treatment is thought to be the generation of ketones, which provide brain cells (neurons and astrocytes) with an energy source that is more efficient than glucose, resulting in beneficial downstream metabolic changes, such as increasing adenosine levels, which might […]

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Outcome Age-Based Prediction of Successful Cognitive Aging by Total Cholesterol

Total cholesterol and cognition associations differ in studies at different outcome ages. Some associations of cholesterol with cognition diminish as outcome age increases. In the oldest-old, some relationships reverse from younger elderly samples. Studies seeking protection should focus on good cognition despite high risk. Some associations of high total cholesterol with dementia risk diminish as […]

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Effect of Depression and Diabetes on the Risk for Dementia

Although depression and type 2 diabetes mellitus (DM) may independently increase the risk for dementia, no studies have examined whether the risk for dementia among people with comorbid depression and DM is higher than the sum of each exposure individually. It was  performed a national population-based cohort study of 2 454 532 adults, including 477 133 (19.4%) with […]

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