Reduced Risk of Dementia in Elderly Tied to Higher Cholesterol Levels

Total cholesterol and cognition associations differ in studies at different outcome ages. Some associations of cholesterol with cognition diminish as outcome age increases. In the oldest-old, some relationships reverse from younger elderly samples. Studies seeking protection should focus on good cognition despite high risk. Some associations of high total cholesterol with dementia risk diminish as […]

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Canola Oil Linked to Worsened Memory and Learning Ability

In recent years consumption of canola oil has increased due to lower cost compared with olive oil and the perception that it shares its health benefits. However, no data are available on the effect of canola oil intake on Alzheimer’s disease (AD) pathogenesis. Herein, we investigated the effect of chronic daily consumption of canola oil […]

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How Does the Ketogenic Diet Work?

The ketogenic diet and its newer variants are clinically useful in treating epilepsy. They can also have antiepileptogenic properties and can eventually have a role in treating other neurologic and nonneurologic conditions. Despite being nearly a century old, identifying the molecular underpinnings of the ketogenic diet has been challenging. However, recent studies provide experimental evidence […]

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The brain-changing benefits of exercise

What’s the most transformative thing that you can do for your brain today? Exercise! says neuroscientist Wendy Suzuki. Get inspired to go to the gym as Suzuki discusses the science of how working out boosts your mood and memory — and protects your brain against neurodegenerative diseases like Alzheimer’s.

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Midlife Hypertension and 20-Year Cognitive Change

Hypertension is a treatable potential cause of cognitive decline and dementia, but its greatest influence on cognition may occur in middle age. The objective of the study was to evaluate the association between midlife (48-67 years of age) hypertension and the 20-year change in cognitive performance. The Atherosclerosis Risk in Communities cohort (1990-1992 through 2011-2013) […]

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Association Between Ultraprocessed Food Consumption and Risk of Mortality

Question  Is high consumption of ultraprocessed food associated with an increase in overall mortality risk? Findings  In this cohort study of 44 551 French adults 45 years or older, a 10% increase in the proportion of ultraprocessed food consumption was statistically significantly associated with a 14% higher risk of all-cause mortality. Meaning  An increase in ultraprocessed food consumption may […]

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A Ketogenic Diet Improves Cognition

Age-related cognitive decline has been linked to a diverse set of neurobiological mechanisms, including bidirectional changes in proteins critical for neuron function. Importantly, these alterations are not uniform across the brain. For example, the hippocampus (HPC) and prefrontal cortex (PFC) show distinct patterns of dysfunction in advanced age. Because higher cognitive functions require large-scale interactions […]

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Diabetes is linked with cognitive dysfunction

Middle-aged adults with diabetes performed worse on assessments of executive function, attention and memory when compared with adults without diabetes, independent of other cardiovascular risk factors and depression status, according to findings from a population-based study. “Recently, attention has been given to modifiable risk factors to help curtail the increasing prevalence of dementia, and several […]

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Ketogenic Diet Shows Promising Results for All Dementia Stages

Studies show a ketogenic diet can slow and even reverse symptoms of memory loss and cognitive impairment throughout all the dementia stages. You might be asking, “What is a ketogenic diet?” A ketogenic diet is a high-fat, adequate-protein, and low-carbohydrate diet that produces ketones—compounds the body can use to produce energy. Ketones have been shown in studies […]

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Evaluation of the Concurrent Trajectories of Cardiometabolic Risk Factors in the 14 Years Before Dementia

Cardiometabolic risk factors have been associated with an increased risk of dementia; yet, the optimal targets and time window for the management of cardiometabolic health to prevent dementia remain unknown. OTo model concurrently and compare the trajectories of cardiometabolic risk factors up to 14 years preceding diagnosis in individuals with dementia and matched controls free […]

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