The Straight Dope on Cholesterol

Cholesterol is one of the most misunderstood molecules in the human body. Much like fire, it can be an essential tool for life, if used properly, or a destructive force if allowed to run amok. In this presentation, Peter Attia will explain how the body creates, moves, and utilizes this vital molecule and how what […]

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Why Cholesterol is Good for You

Dr. Terry Wahls is a professor of medicine at the University of Iowa where she conducts clinical research on the use of diet and lifestyle to treat brain-related problems. She has also worked at the VA for many years in the traumatic brain injury clinic and was the director of the therapeutic lifestyle clinic. In […]

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The Toll of America’s Obesity

Beyond the human suffering, diet-related diseases impose massive economic costs. Obesity rates in the United States continue to worsen. So, too, does economic inequality. Are these trends related? After remaining essentially flat in the 1950s and 1960s, the prevalence of obesity doubled in adults and tripled in children between the 1970s and 2000. According to new data from the Centers […]

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Carbotoxicity

Modern nutrition is often characterized by the excessive intake of different types of carbohydrates ranging from digestible polysaccharides to refined sugars that collectively mediate noxious effects on human health, a phenomenon that we refer to as “carbotoxicity.” Epidemiological and experimental evidence combined with clinical intervention trials underscore the negative impact of excessive carbohydrate uptake, as […]

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An Engineering View of Modern Chronic Disease Prevention

Ivor Cummins BE(Chem) CEng MIEI PMP® completed a Chemical Engineering degree at UCD in 1990. He has since spent over 25 years in corporate technical leadership and management positions, and was shortlisted in 2015 as one of the top 6 of 500 applicants for “Irish Chartered Engineer of the Year”. Ivor’s focus and specialty is […]

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An Update on Glucose Toxicity

Chronic exposure of glucose rich environment creates several physiological and pathophysiological changes. There are several pathways by which hyperglycemia exacerbate its toxic effect on cells, tissues and organ systems. Hyperglycemia can induce oxidative stress, upsurge polyol pathway, activate protein kinase C (PKC), enhance hexosamine biosynthetic pathway (HBP), promote the formation of advanced glycation end-products(AGEs) and finally alters gene expressions. Prolonged hyperglycemic condition leads to severe diabetic condition by […]

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Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress

Intermittent fasting (IF) improves cardiometabolic health; however, it is unknown whether these effects are due solely to weight loss. We conducted the first supervised controlled feeding trial to test whether IF has benefits independent of weight loss by feeding participants enough food to maintain their weight. Our proof-of-concept study also constitutes the first trial of […]

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Stress Raises Cholesterol Levels

It appears so for some people, according to a new study that examines how reactions to stress over a period of time can raise a person’s lipid levels. This finding is reported in the November issue of Health Psychology, published by the American Psychological Association (APA). In a sample of 199 healthy middle-aged men and women, […]

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