On the keto diet? Ditch the cheat day

“The ketogenic — or keto — diet has become very common for weight loss or to manage diseases like type 2 diabetes,” says Jonathan Little, associate professor in the School of Health and Exercise Sciences at UBCO and study senior author. “It consists of eating foods rich in fats, moderate in protein, but very low […]

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Hypoascorbemia induces atherosclerosis and vascular deposition of lipoprotein(a)

Lipoprotein(a), a variant of LDL carrying the adhesive glycoprotein apo(a), is a leading risk factor for cardiovascular disease. Lipoprotein(a) (Lp(a)) is found in humans and subhuman primates but rarely in lower mammals. Better understanding of the evolutionary advantage of this molecule should elucidate its physiological role. We developed a new mouse model with two characteristics […]

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Everybody Who Eats Needs To Hear This Warning | David Perlmutter on Health Theory

Dr. David Perlmutter is a Board-Certified Neurologist and the author of the #1 New York Times bestseller Grain Brain. In this episode of Health Theory, he and host Tom Bilyeu discuss the important health metrics to pay attention to, how lifestyle affects health, and the importance of connection.  

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Prolonged Fasting Increases Cell Regeneration and Reverse Immunosuppression

Immune system defects are at the center of aging and a range of diseases. Here, we show that prolonged fasting reduces circulating IGF-1 levels and PKA activity in various cell populations, leading to signal transduction changes in long-term hematopoietic stem cells (LT-HSCs) and niche cells that promote stress resistance, self-renewal, and lineage-balanced regeneration. Multiple cycles […]

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Fasting Regenerates Your Entire Immune System

Prolonged fasting downregulates a IGF-1/PKA pathway in stem Prolong fasting protects hematopoietic cells from chemotoxicity Prolonged fasting cycles promote HSC self-renewal to reverse immunosuppression Inhibition of IGF-1 or PKA signaling mimics the effects of prolonged Immune system defects are at the center of aging and a range of diseases. Here, we show that prolonged fasting […]

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Does Fat Really Burn in the Flame of Carbohydrate?

Dr. Michael R. Eades received his BSCE degree in Civil Engineering from California Polytechnic University (Cal Poly), Pamona, California and his MD from the University of Arkansas Medical Sciences (UAMS). After completing training in General Surgery as UAMS, Dr. Eades (along with his wife) founded Medi-Stat Medical Clinics, a chain of general family medicine outpatient […]

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Substantial and Sustained Improvements in Blood Pressure, Weight and Lipid Profiles from a Carbohydrate Restricted Diet: An Observational Study of Insulin Resistant Patients in Primary Care

Hypertension is the second biggest known global risk factor for disease after poor diet; perhaps lifestyle interventions are underutilized? In a previous small pilot study, it was found that a low carbohydrate diet was associated with significant improvements in blood pressure, weight, ‘deprescribing’ of medications and lipid profiles. We were interested to investigate if these […]

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Why We Get Fat

Gary Taubes is an award-winning journalist and author of “Why We Get Fat: And What to do About It.” Here, he speaks on “Good Calories, Bad Calories: Challenging the Conventional, Wisdom on Diet, Weight Control, and Disease” at The Ohio State University’s Ohio Union on April 12, 2011.  

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