Why We Get Fat

Gary Taubes is an award-winning journalist and author of “Why We Get Fat: And What to do About It.” Here, he speaks on “Good Calories, Bad Calories: Challenging the Conventional, Wisdom on Diet, Weight Control, and Disease” at The Ohio State University’s Ohio Union on April 12, 2011.  

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The Sugar-Cancer Connection

Nuclear accumulation of β-catenin, a widely recognized marker of poor cancer prognosis, drives cancer cell proliferation and senescence bypass and regulates incretins, critical regulators of fat and glucose metabolism. Diabetes, characterized by elevated blood glucose levels, is associated with increased cancer risk, partly because of increased insulin growth factor 1 signaling, but whether elevated glucose […]

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Targeting Insulin Inhibition as a Metabolic Therapy in Advanced Cancer

Most aggressive cancers demonstrate a positive positron emission tomographic (PET) result using ¹⁸F-2-fluoro-2-deoxyglucose (FDG), reflecting a glycolytic phenotype. Inhibiting insulin secretion provides a method, consistent with published mechanisms, for limiting cancer growth.Eligible patients with advanced incurable cancers had a positive PET result, an Eastern Cooperative Oncology Group performance status of 0 to 2, normal organ […]

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Obesity and Cancer

Excess body weight (overweight and obesity) is characterized by chronic hyperinsulinaemia and insulin resistance, and is implicated both in cancer risk and cancer mortality. The list of cancers at increased risk of development in an “obesogenic” environment include common adult cancers such as endometrium, post-menopausal breast, colon and kidney, but also less common malignancies such […]

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Juice Is Not Healthy

Obesity affects 40 percent of adults and 19 percent of children in the United States and accounts for more than $168 billion in health care spending each year. Sugary beverages are thought to be one of the major drivers of the obesity epidemic. These drinks (think soda and sports drinks) are the largest single source […]

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Fasting and Its Impact on Skin Anatomy, Physiology, and Physiopathology

Skin serves as the first protective line and barrier of the body. Like many other organs, skin can be affected by several disorders in response to external factors such as pathogens, ultraviolet light, and pollution, as well as endogenous alterations related to aging and/or oxidative stress disturbance. Researchers have reported new insights into how skin […]

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Sugar: The Bitter Truth

Watch “The Skinny on Obesity” with Dr. Lustig: http://www.uctv.tv/skinny-on-obesity Robert H. Lustig, MD, UCSF Professor of Pediatrics in the Division of Endocrinology, explores the damage caused by sugary foods. He argues that fructose (too much) and fiber (not enough) appear to be cornerstones of the obesity epidemic through their effects on insulin. Series: UCSF Mini […]

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Glyphosate Induces Human Breast Cancer Cells Growth via Estrogen Receptors

Glyphosate is an active ingredient of the most widely used herbicide and it is believed to be less toxic than other pesticides. However, several recent studies showed its potential adverse health effects to humans as it may be an endocrine disruptor. This study focuses on the effects of pure glyphosate on estrogen receptors (ERs) mediated […]

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The Power of a Ketogenic Diet to Reverse Disease with Dr. Sarah Hallberg

Dr. Sarah Hallberg is a diabetes expert, who is here to change the way we treat diabetes. Her number one weapon for reversing type 2 diabetes: a ketogenic diet. Dr. Hallberg is a Medical Director at Virta Health and a Fellow of the Aspen Institute’s Health Innovator Fellowship and a member of the Aspen Global […]

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Emerging Evidence on Intermittent Fasting and Calorie Restriction Mimetics

There is growing interest in harnessing lifestyle and pharmaceutical interventions to boost immune function, reduce tumor growth, and improve cancer treatment efficacy while reducing treatment toxicity. Interventions targeting glucose metabolism are particularly promising, as they have the potential to directly inhibit tumor cell proliferation. However, because anti-tumor immune effector cells also rely on glycolysis to […]

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