Cannabidiol increases the nociceptive threshold in a preclinical model of Parkinson’s disease

Highlights• The CBD treatment decreases hyperalgesia and allodynia in experimental parkinsonism. • The inverse agonist of the CB1 receptor prevents the antinociceptive effect of CBD. • FAAH inhibitor or TRPV1 antagonist potentiates the CBD antinociceptive effect. Abstract Medications that improve pain threshold can be useful in the pharmacotherapy of Parkinson’s disease (PD). Pain is a […]

Read More »

On the keto diet? Ditch the cheat day

“The ketogenic — or keto — diet has become very common for weight loss or to manage diseases like type 2 diabetes,” says Jonathan Little, associate professor in the School of Health and Exercise Sciences at UBCO and study senior author. “It consists of eating foods rich in fats, moderate in protein, but very low […]

Read More »

Hypoascorbemia induces atherosclerosis and vascular deposition of lipoprotein(a)

Lipoprotein(a), a variant of LDL carrying the adhesive glycoprotein apo(a), is a leading risk factor for cardiovascular disease. Lipoprotein(a) (Lp(a)) is found in humans and subhuman primates but rarely in lower mammals. Better understanding of the evolutionary advantage of this molecule should elucidate its physiological role. We developed a new mouse model with two characteristics […]

Read More »

Life long choline supplementation may improve cognitive function in Alzheimer’s patients, finds study

Life long choline supplementation may improve cognitive function in Alzheimer’s patients, revealed a study published in the journal, Aging Cell.  Researchers from ASU-Banner Neurodegenerative Disease Research Center (NDRC) checked whether choline supplementation could alleviate the alleviate effect of Alzheimer’s disease. Choline acts to protect the brain from Alzheimer’s disease in at least two ways, both […]

Read More »

Sugar is Not a Treat

Sugar is hiding everywhere in today’s widely-accepted diet, but meanwhile its devastating effects are creating more deaths than automobile accidents. In this eye-opening talk, Dr. Jody Stanislaw, a Naturopathic Doctor who has been studying the negative effects of sugar since being diagnosed with type 1 diabetes at the age of 7, dives into how the […]

Read More »

Everybody Who Eats Needs To Hear This Warning | David Perlmutter on Health Theory

Dr. David Perlmutter is a Board-Certified Neurologist and the author of the #1 New York Times bestseller Grain Brain. In this episode of Health Theory, he and host Tom Bilyeu discuss the important health metrics to pay attention to, how lifestyle affects health, and the importance of connection.  

Read More »

Bread and Other Edible Agents of Mental Disease

Perhaps because gastroenterology, immunology, toxicology, and the nutrition and agricultural sciences are outside of their competence and responsibility, psychologists and psychiatrists typically fail to appreciate the impact that food can have on their patients’ condition. Here we attempt to help correct this situation by reviewing, in non-technical, plain English, how cereal grains—the world’s most abundant […]

Read More »

Chronic Inflammation Removes Motivation by Reducing Dopamine in the Brain

Why do we feel listless when we are recovering from an illness? The answer is, apparently, that low-grade chronic inflammation interferes with the dopaminergic signaling system in the brain that motivates us to do things. This was reported in a new paper published in the journal Trends in Cognitive Sciences. The research carried out at Emory […]

Read More »

Low Serum Concentrations of Vitamin B6 and Iron Are Related to Panic Attack and Hyperventilation Attack

Patients undergoing a panic attack (PA) or a hyperventilation attack (HVA) are sometimes admitted to emergency departments (EDs). Reduced serotonin level is known as one of the causes of PA and HVA. Serotonin is synthesized from tryptophan. For the synthesis of serotonin, vitamin B6 (Vit B6) and iron play important roles as cofactors. To clarify […]

Read More »