Supra-Additive Effects of Combining Fat and Carbohydrate on Food Reward

Fat and carbohydrate interact to potentiate reward independently of liking. This is reflected in supra-additive responses in the striatum during food valuation. Participants are able to estimate energy density from fat, but not carbohydrate. Accurate estimation of energy density recruits a prefrontal-fusiform gyrus circuit Post-ingestive signals conveying information about the nutritive properties of food are […]

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Metabolic Syndrome, Insulin Resistance, and Cognitive Dysfunction: Does Your Metabolic Profile Affect Your Brain?

Dementia and type 2 diabetes are both characterized by long prodromal phases, challenging the study of potential risk factors and their temporal relation. The progressive relation among metabolic syndrome, insulin resistance (IR), and dementia has recently been questioned, wherefore the aim of this study was to assess the potential association among these precursors of type […]

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Megan Ramos – ‘Practical Fasting: The Use of Therapeutic Fasting in a Clinical Setting’

Megan Ramos is the President and Co-Founder of the Intensive Dietary Management Program based in Toronto in Ontario, Canada. Megan attended the University of Toronto where she did clinical research in the field of nephrology and developed a strong interest in preventative medicine. For the last nineteen years Megan has worked alongside Dr. Jason Fung […]

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American Toddlers Consume Too Much Added Sugar

A new study suggests children in the US begin consuming added sugar at a very young age and that many toddlers’ sugar intake exceeds the maximum amount recommended for adults. The study found 99 percent of a representative sample of US toddlers age 19-23 months consumed an average of just over 7 teaspoons of added sugar on […]

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Arsenic, Lead Found in Popular Protein Supplements

Clean Label Project™ completed a study of 134 protein powder products from 52 brands. Products were screened for over 130 toxins including heavy metals, BPA, pesticides, and other contaminants with links to cancer and other health conditions. PRODUCTS Clean Label Project had the top-selling protein powder products – animal-based, whey, and plant-based – tested and reviewed […]

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What is Metabolic Syndrome, and Why are Children Getting It?

Metabolic syndrome, sometimes known by other names, is a clustering of at least three of the five following medical conditions: abdominal obesity, high blood pre.ssure, high blood sugar, high serum triglycerides and low high-density lipoprotein (HDL) levels. Metabolic syndrome is associated with the risk of developing cardiovascular disease and type 2 diabetes. In the US about a quarter of the adult population has metabolic syndrome, and the prevalence increases […]

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Antidepressant Use May Contribute to Long-Term Population Weight Gain

Researchers at King’s College London have found that patients prescribed any of the 12 most commonly used antidepressants were 21% more likely to experience an episode of gain weight than those not taking the drugs, (after adjusting for other factors which might affect this result). The full research is published in the BMJ. They also found […]

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Triglycerides cross the blood–brain barrier and induce central leptin and insulin receptor resistance

Resistance at the brain receptors for leptin and insulin has been associated with increased feeding, obesity and cognitive impairments. The causal agent for central resistance is unknown but could be derived from the blood. Here we postulate whether hypertriglyceridemia, the major dyslipidemia of the metabolic syndrome, could underlie central leptin and insulin resistance. Design:  We […]

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Distinct Circadian Signatures in Liver and Gut Clocks Revealed by Ketogenic Diet

• KD induces tissue-specific reprogramming of the circadian clock in liver and gut • KD induces an increase in liver BMAL1 chromatin recruitment and amplitude of CCGs • KD drives tissue-specific oscillation of PPARα and its target genes • Oscillation of βOHB in gut and serum parallels gut-specific cycling of H3 acetylation The circadian clock […]

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