Alzheimer’s Disease to Double by 2060

Nearly 14 million Americans may have Alzheimer’s disease by then. Over 3% of the population — nearly 14 million Americans — may have Alzheimer’s disease or related dementias by 2060, according to a new CDC report. The burden of Alzheimer’s disease and related dementias, which was 1.6% of the U.S. population in 2014, is projected […]

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Is Alzheimer’s Disease Actually Type 3 Diabetes?

For the first time, scientists have found a connection between abnormalities in how the brain breaks down glucose and the severity of the signature amyloid plaques and tangles in the brain, as well as the onset of eventual outward symptoms, of Alzheimer’s disease. The study was supported by the National Institute on Aging (NIA), part […]

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White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer’s Disease

White matter degeneration is a pathological hallmark of neurodegenerative diseases including Alzheimer’s. Age remains the greatest risk factor for Alzheimer’s and the prevalence of age-related late onset Alzheimer’s is greatest in females. We investigated mechanisms underlying white matter degeneration in an animal model consistent with the sex at greatest Alzheimer’s risk. Results of these analyses […]

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White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer’s Disease

White matter degeneration is a pathological hallmark of neurodegenerative diseases including Alzheimer’s. Age remains the greatest risk factor for Alzheimer’s and the prevalence of age-related late onset Alzheimer’s is greatest in females. We investigated mechanisms underlying white matter degeneration in an animal model consistent with the sex at greatest Alzheimer’s risk. Results of these analyses […]

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Exercise for cognitive brain health in aging

We systematically appraised randomized controlled trials proposing exercise to influence cognition in older adults to (1) assess the methodologic quality using Cochrane criteria; (2) describe various exercise dose measures and assess their relationship with improved cognitive performance; and (3) identify consistent patterns of reported effects on cognition. There was overall good methodologic quality in all […]

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Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets

Very-low-carbohydrate diets or ketogenic diets have been in use since the 1920s as a therapy for epilepsy and can, in some cases, completely remove the need for medication. From the 1960s onwards they have become widely known as one of the most common methods for obesity treatment. Recent work over the last decade or so […]

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What Will Happen to Your Body If You Walk Every Day

Walking is a totally free, easy exercise that requires little effort, and benefits not only your physical but also your mental well-being. If you’re looking for a simple yet very effective way of losing weight and improving your overall health, walking is something just for you. People who are physically active throughout their life are […]

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Evidence for Altered Insulin Receptor Signaling in Alzheimer’s Disease

Highlights • Metabolic disease increases the risk of developing cognitive decline and dementia. • AD is associated with peripheral metabolic alterations. • Insulin/insulin sensitivity is altered in the AD brain. • Insulin and Insulin sensitizers can improve cognitive function in AD. Abstract Epidemiological data have shown that metabolic disease can increase the propensity for developing […]

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CarbLoaded: A Culture Dying to Eat

The film traces the origins of our beliefs about healthful and unhealthful food. Experts from all over the world talk about the problems as well as short and long term solutions. Among the many experts in the film are authors like Gary Taubes, Mark Sisson, and Melanie Warner. Medical doctors such as David Perlmutter M.D., […]

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